Antonio Siccardi

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Antonio G. Siccardi (born October 1, 1944 in Varese ) is an Italian immunologist and virologist .

Siccardi graduated from the Faculty of Medicine at the University of Pavia and graduated in 1968. He later became an assistant professor for genetics (1973 to 1980) and then for microbiology (1974 to 1980). After a short research stay as a full professor in Rome (1980 to 1982), he was appointed full professor of molecular immunology at the University of Milan . From 1990 to 1994 he was the operational director of the DIBIT research institute in Milan. From 1991 to 1998 he coordinated HIV / AIDS research at the Research Institute of the Ospedale San Raffaele at the University of Milan. He is (2015) Professor at the University of Milan at the Research Institute of the Ospedale San Raffaele . Siccardi is a member of the council of the Istituto Nazionale di Genetica Molecolare (INGM). From 2000 to 2008 he was Deputy Professor of Genetics at the Psychological Faculty of the Università Vita-Salute San Raffaele in Milan and from 2006 he was Deputy Professor of the History of Genetics at the Biotechnology Faculty of the Università Vita Salute San Raffaele .

Siccardi is married to Giovanna Viale, biologist and professor at the Center of the University and High School of Milan-for Bioscience education (CusMiBio) in Milan.

research

Siccardi conducts research with a focus on the molecular immunology of HIV , influenza , cancer (especially mesothelioma ), immunoglobulin E , and vaccine design based on recombinant modified vaccinia Ankara viruses (MVA) or birdpox viruses . Siccardi developed a recombinant MVA-based vaccination vector with different fluorescent reporter genes , which indicate the course of its recombination with the transgene of an antigen (green, colorless, red).

Individual evidence

  1. ^ A b c d e CV of Antonio Siccardi . University of Milan.
  2. ^ Jannis Kounellis per il charity project "all'Arte" (Italian). Vogue Uomo Italy, May 22nd, 2014.
  3. ↑ F. Grassi, R. Meneveri, M. Gullberg, L. Lopalco, GB Rossi, P. Lanza, C. De Santis, G. Brattsand, S. BUTTO, E. Ginelli, AG Siccardi: Human immunodeficiency virus type 1 gp120 mimics a hidden monomorphic epitope borne by class I major histocompatibility complex heavy chains. In: The Journal of experimental medicine. Volume 174, Number 1, July 1991, ISSN  0022-1007 , pp. 53-62, PMID 1711567 , PMC 2118897 (free full text).
  4. ↑ G. Scarlatti, E. Tresoldi, A. Björndal, R. Fredriksson, C. Colognesi, HK Deng, MS Malnati, A. Plebani, AG Siccardi, DR Littman, EM Fenyö, P. Lusso: In vivo evolution of HIV 1 co-receptor usage and sensitivity to chemokine-mediated suppression. In: Nature medicine. Volume 3, Number 11, November 1997, ISSN  1078-8956 , pp. 1259-1265, PMID 9359702 .
  5. ↑ E. Soprana, M. Panigada, M. Knauf, A. Radaelli, L. Vigevani, A. Palini, C. Villa, M. Malnati, G. Cassina, Reinhard Kurth , S. Norley, AG Siccardi: joint production of prime / boost pairs of Fowlpox Virus and Modified Vaccinia Ankara recombinants carrying the same transgene. In: Journal of virological methods. Volume 174, number 1-2, June 2011, ISSN  1879-0984 , pp. 22-28, doi : 10.1016 / j.jviromet.2011.03.013 , PMID 21419167 .
  6. ↑ L. Vangelista, E. Soprana, M. Cesco-Gaspere, P. Mandiola, G. Di Lullo, RN Fucci, F. Codazzi, A. Palini, G. Paganelli, OR Burrone, AG Siccardi: Membrane IgE binds and activates Fc epsilon RI in an antigen-independent manner. In: Journal of Immunology (Baltimore, Md.: 1950). Volume 174, Number 9, May 2005, ISSN  0022-1767 , pp. 5602-5611, PMID 15843559 .
  7. ↑ G. Di Lullo, E. Soprana, M. Panigada, A. Palini, Volker Erfle, C. Staib, G. Sutter, AG Siccardi: Marker gene swapping facilitates recombinant Modified Vaccinia Virus Ankara production by host-range selection. In: Journal of virological methods. Volume 156, number 1-2, March 2009, ISSN  0166-0934 , pp. 37-43, doi : 10.1016 / j.jviromet.2008.10.026 , PMID 19038289 .
personal data
SURNAME Siccardi, Antonio
ALTERNATIVE NAMES Siccardi, Antonio Gennaio (full name)
BRIEF DESCRIPTION Italian immunologist and virologist
DATE OF BIRTH October 1, 1944
PLACE OF BIRTH Varese