Asteroid hyalosis

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Asteroid hyalosis in a Yorkshire Terrier

The asteroid hyalosis is a degenerative phenomenon of the eye, in which small milky white opacities form in the vitreous humor of the eye . It is described in humans, dogs, and chinchillas. From a clinical point of view, the opacities are highly refractive, which makes them appear like stars or meteorites in the night sky.

Such "stars" are to be distinguished from the widespread floaters , which are fibrillary or cellular coagulates that form in the vitreous humor. Exact causes for the development of asteroid hyalosis are not known, but there seem to be connections with the occurrence of diabetes mellitus , high blood pressure, hypercholesterolemia and, in some animals, tumors of the ciliary body . Asteroid hyalosis appears to be a typical aging phenomenon in dogs that are kept.

The deposits consist of hydroxyapatite, which in turn is formed from calcium and phosphates or phosphated lipids. Although asteroid hyalosis does not normally cause serious impairment of vision, the opacities can be very annoying. They also affect examinations and measurements of the retina . Normally, asteroid hyalosis does not require treatment, but vitreous removal may be indicated in individual cases for diagnostic and therapeutic reasons.

Individual evidence

  1. ^ Mingan Wang, Peter F. Kador, Milton Wyman: Structure of asteroid bodies in the vitreous of galactose-fed dogs. In: Molecular Vision. Vol. 12, April 2006, pp. 283-289, PMID 16617295 , online .
  2. A. Akram, MK Niazi, M. Ishaq, N. Azad: Frequency of diabetics in asteroid hyalosis patients. In: Journal of Ayub Medical College. Abbottabad, Pakistan. Volume 15, No. 3, July / September 2003, ISSN  1025-9589 , pp. 10-11, PMID 14727330 .
  3. ^ R. Bergren, G. Brown, J. Duker: Prevalence and association of asteroid hyalosis with systemic diseases. In: American Journal of Ophthalmology. Volume 111, No. 3, March 1991, ISSN  0002-9394 , pp. 289-293, PMID 2000898 .
  4. Kirk N. Gelatt (Ed.): Veterinary Ophthalmology. 3rd edition. Lippincott Williams & Wilkins, Philadelphia PA et al. a. 1999, ISBN 0-683-30076-8 .
  5. Ellen Bjerk: Ocular Disease of the Aging Dog . In: Proceedings of the 29th World Congress of the World Small Animal Veterinary Association . 2004. Retrieved March 23, 2007.
  6. Hitoshi Komatsu, Yumi Kamura, Kuniko Ishi, Yoji Kashima: Fine structure and morphogenesis of asteroid hyalosis. In: Medical Electron Microscopy. Volume 36, No. 2, June 2003, ISSN  0918-4287 , pp. 112-119, PMID 12825125 , doi: 10.1007 / s00795-002-0211-y .
  7. ^ SCK Wong, R. Sampath: Erroneous automated refraction in a case of asteroid hyalosis. In: Journal of Cataract and Refractive Surgery . Volume 28, No. 9, September 2002, ISSN  0886-3350 , pp. 1707-1708, PMID 12231337 , doi: 10.1016 / S0886-3350 (01) 01224-X .
  8. J. Olea Vallejo, E. Muñoz Corrales, J. Mateos Poch, P. Mulet Perera, M. Suñer Capo: Vitrectomía en hialosis asteroidea. In: Archivos de la Sociedad Española de Oftalmología. Volume 77, No. 4, 2002, ISSN  0365-6691 , pp. 201-204, PMID 11973661 .
  9. ^ R. Feist, R. Morris, C. Witherspoon, N. Blair, B. Ticho, M. White: Vitrectomy in asteroid hyalosis. In: Retina. Vol. 10, No. 3, 1990, ISSN  0275-004X , pp. 173-177, PMID 2236940 .