Axel Radlach Pries

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Axel Radlach Pries (born February 20, 1954 in Cologne , Germany ) is a German physician, professor of physiology and currently (as of 2018) dean and member of the board of the Charité - Universitätsmedizin Berlin . He is married to the photographer Gina Elisabeth Pries.

Education and functions

From 1964 to 1972 Axel R. Pries attended the Friedrich-Wilhelm-Gymnasium in Cologne. In 1979 Axel Pries passed his medical state examination at the University of Cologne and obtained his doctorate in the following year. med. (summa cum laude). Axel Pries worked as a research assistant at the University of Cologne until 1983 , and then at the Institute for Physiology at the Free University of Berlin , from 1985 as a university assistant (C1). In July 1990 he completed his habilitation in physiology at the Free University of Berlin and became senior assistant (C2) at the Institute of Physiology and, from 1995, an adjunct professor. From 1997 to 1998 Axel Pries worked as senior anesthetist at the German Heart Center Berlin (DHZB), and at the end of 1998 he became professor (C3) at the Institute of Physiology at the Free University of Berlin. From 2001 to 2015 he was director of the Physiological Institute at Charité - Universitätsmedizin Berlin . Since 2015 he has been dean and member of the board of directors of Charité - Universitätsmedizin Berlin as well as board member of the Berlin Institute for Health Research (BIG); since 2018 he has been interim chairman of the board of BIG.

From 1984 to 2014, Axel Pries was a consultant for NIH projects with Tim Secomb at the University of Arizona in Tucson, and as part of this activity, Pries spent a month doing research at the University of Arizona.

Scientific focus

His scientific focus includes the areas of microcirculation , organ perfusion , endothelial function, endothelial surface, vascular remodeling , angiogenesis , tumor microcirculation and blood rheology .

Prices

  • 1980: “Hochhausstiftung” doctoral award, University of Cologne
  • 1986: Abbott Microcirculation Award, European Society for Microcirculation
  • 1995: Lafon Hemorheology-Microcirculation Award, International Society for Clinical Haemorheology
  • 2000: Fellow, European Society of Cardiology
  • 2008: Visiting Fellowship, Isaac Newton Institute for Mathematical Sciences, Cambridge / UK
  • 2008: Asian Union for Microcirculation Prize
  • 2011: Malpighi Award, European Society for Microcirculation
  • 2015: William Harvey Basic Science Lecture and Silver Medal, European Society of Cardiology (ESC)
  • 2015: Kitanomaru Award, 10th World Conf. for Microcirculation, Kyoto, Japan
  • 2018: Poiseuille Gold Medal, International Society of Biorheology

Functions in scientific societies

Axel Pries was secretary of the Society for Microcirculation from 1996 to 2011, and Secretary General of the European Society for Microcirculation (ESM) from 1998 to 2011. In the European Society of Cardiology , Pries held various management positions from 1998: from 1998 to 2000 he was Chairman of the "Working Group on Coronary Pathophysiology and Microcirculation", from 2005 to 2010 and again from 2012 to 2014 Coordinator for Basic Science in the Congress Program Committee and from 2010 to 2012 Chair of the Council for Basic Cardiovascular Science (CBCS). From 2006 to 2015 he was chairman of the global coordinating body for microcirculation, the International Liaison Committee for Microcirculation (ILCM). Since 2017 he has been a member of the board of the Alliance for Biomedical Research in Europe , the umbrella organization of the major bio-medical societies in Europe. From 2018 to 2019 he will be president of this organization.

Publications

  • Coronary microcirculatory pathophysiology: can we afford it to remain a black box? Pries AR and Reglin B. European Heart Journal 2017 Feb 14; 38 (7): 478-488.
  • Coronary vascular regulation, remodeling, and collateralization: mechanisms and clinical implications on behalf of the working group on coronary pathophysiology and microcirculation. Pries AR, et al. European Heart Journal 2015; 36 (45): 3134-3146.
  • Making microvascular networks work: angiogenesis, remodeling, and pruning. Praised AR and Secomb TW. Physiology (Bethesda) 2014; 29 (6): 446-455.
  • Metabolic control of microvascular networks: oxygen sensing and beyond. Reglin B and Pries AR. J Vasc Res 2014; 51 (5): 376-392.
  • Presentation, management, and outcomes of ischemic heart disease in women. Vaccarino V, Badimon L, Corti R, de Wit C, Dorobantu M, Manfrini O, Koller A, Pries A, Cenko E, Bugiardini R. Nature Rev Cardiol 2013; 10 (9): 508-518.
  • Angiogenesis: an adaptive dynamic biological patterning problem. Secomb TW, Alberding JP, Hsu R, Dewhirst MW, Pries AR. PLoS Comput Biol 2013; 9 (3): e1002983.
  • Precapillary oxygenation contributes relevantly to gas exchange in the intact lung. Tabuchi A, Styp-Rekowska B, Slutsky AS, Wagner PD, Pries AR *, Kuebler WM * (* these authors share senior authorship). Am J Respir Crit Care Med 2013; 188 (4): 474-481.
  • Excessive erythrocytosis compromises the blood-endothelium interface in erythropoietin-overexpressing mice. Richter V, Savery MD, Gassmann M, Baum O, Damiano ER, Pries AR. J Physiol 2011; 589 (21): 5181-5192.
  • Pulsatile shear and Gja5 modulate arterial identity and remodeling events during flow-driven arteriogenesis. Buschmann I *, Pries A *, Styp-Rekowska B et al. (* these authors contributed equally). Development 2010; 137 (13): 2187-2196.
  • The shunt problem: control of functional shunting in normal and tumor vasculature. Pries AR, Hopfner M, Le Noble F, Dewhirst MW, Secomb TW. Nature Rev Cancer 2010; 10 (8): 587-593.
  • Origins of heterogeneity in tissue perfusion and metabolism. Praised AR and Secomb TW. Cardiovasc Res 2009; 81 (2): 328-335.
  • Blood flow in microvascular networks. Praised AR and Secomb TW. In: Handbook of Physiology: Microcirculation, edited by Tuma RF, Durán WN and Ley K., Elsevier, 2008, Chap 1, 3-36.
  • Remodeling of blood vessels: responses of diameter and wall thickness to hemodynamic and metabolic stimuli. Pries AR, Reglin B, Secomb TW. Hypertension 2005; 46 (4): 726-731.
  • The endothelial surface layer . Pries AR, Secomb TW, Gaehtgens P. Pflugers Arch 2000; 440 (5): 653-666.
  • Design principles of vascular beds. Pries AR, Secomb TW, Gaehtgens P. Circ Res 1995; 77 (5): 1017-1023. 3
  • Resistance to blood flow in microvessels in vivo . Pries AR, Secomb TW, Gessner T, Sperandio MB, Gross JF, Gaehtgens P. Circ Res 1994; 75 (5): 904-915.

Individual evidence

  1. ^ Charité - Universitätsmedizin Berlin 2011: Person-Detail . In: Charité - Universitätsmedizin Berlin . ( charite.de [accessed June 29, 2017]).
  2. Axel Radlach Pries: Investigations on the rheology of capillary flow: separation of the corpuscular and plasmatic phase at the capillary entry .
  3. ^ Berlin Institute for Health Research - Charité and Max Delbrück Center: Board of Directors. May 4, 2016. Retrieved August 5, 2017 .
  4. ^ University of Arizona. Retrieved October 20, 2017 .
  5. Super User: The Malpighi Award. Retrieved August 5, 2017 (UK English).
  6. ^ Special Lectures of the ESC. Retrieved August 5, 2017 .
  7. ^ Society for Vascular Biology and Microcirculation. Retrieved October 20, 2017 .
  8. ^ European Society for Microcirculation. Retrieved October 20, 2017 .
  9. ^ Structure. Retrieved August 5, 2017 .
  10. ^ International Liaison Committee for Microcirculation. Retrieved October 20, 2017 .
  11. ^ Members of the International Liaison Committee for Microcirculation (ILC). Retrieved August 5, 2017 .
  12. ^ Alliance for Biomedical Research in Europe (BioMed Alliance). Retrieved October 20, 2017 .
  13. ^ Super Utilisateur: Biomed Europe - Board of Directors. Retrieved August 5, 2017 (UK English).