Bacteriolytic

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A bacteriolytic (also called bacteriolytic agents ) describes substances that mediate the death of a bacterial cell through lysis . Bacteriolytics are bactericides .

properties

The lysis can e.g. B. caused by a dissolution of the cell wall or by inhibiting cell wall synthesis. Antibiotics that inhibit cell wall synthesis, such as penicillin , and chemicals that destroy the cytoplasmic membrane of bacteria are summarized under the term bacteriolytic. Some bacteriocins and bacteriophages are bacteriolytic. The proteins lysozyme and the membrane attack complex produced by animals serve to defend against bacterial pathogens by perforating the cell wall.

literature

  • MT Madigan, JM Martinko (2006): Brock Biology of Microorganisms , Pearson Prentice Hall, Upple Saddle River, NJ07458, ISBN 0-13-196893-9

Individual evidence

  1. ↑ NV Vasilyeva, IM Tsfasman, IV Kudryakova, NE Suzina, NA Shishkova, IS Kulaev, OA Stepnaya: The role of membrane vesicles in secretion of Lysobacter sp. bacteriolytic enzymes. In: Journal of molecular microbiology and biotechnology. Volume 23, number 1-2, 2013, pp. 142-151, ISSN  1660-2412 . doi : 10.1159 / 000346550 . PMID 23615202 .
  2. ↑ S. Matsuzaki, M. Rashel, J. Uchiyama, S. Sakurai, T. Ujihara, M. Kuroda, M. Ikeuchi, T. Tani, M. Fujieda, H. Wakiguchi, S. Imai: Bacteriophage therapy: a revitalized therapy against bacterial infectious diseases. In: Journal of Infection and Chemotherapy Volume 11, Number 5, October 2005, pp. 211-219, ISSN  1341-321X . doi : 10.1007 / s10156-005-0408-9 . PMID 16258815 .
  3. ↑ PW Taylor: Bactericidal and bacteriolytic activity of serum against gram-negative bacteria. In: Microbiological reviews. Volume 47, Number 1, March 1983, pp. 46-83, ISSN  0146-0749 . PMID 6343827 . PMC 281561 (free full text).