Basal rate

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In drug therapy , the basal rate is the amount of a continuously administered, short-acting active ingredient . It covers the basic requirement for the amount of active ingredient. Basal rates are mainly used in insulin therapy with insulin pumps as well as in anesthesia , pain therapy and intensive medicine , for example as continuous epidural analgesia with infusion or syringe pumps .

The advantage of a continuous administration of active ingredient is the constant maintenance of an active ingredient level, which is better suited to the needs. Disadvantages are the increased outlay on equipment and the risk of infections when a parenteral access is used for a longer period of time .

The basal rate can also be varied depending on the time of day. In phases of increased need for active ingredients - for example after food consumption during insulin therapy or acute pain during continuous pain therapy - the amount of active ingredient can be increased by giving an additional dose ( bolus ).

literature

  • Wolfgang Piper: Internal Medicine. Springer 2006, ISBN 9783540337256 , p. 458.
  • Peter Hurter et al .: Compendium of Pediatric Diabetology . Springer 2006, ISBN 9783540400592 , p. 278.
  • Sebastian Schulz-Stübner: Regional anesthesia and analgesia: techniques and therapy schemes for practice . Schattauer Verlag 2003, ISBN 9783794521920 .