Blood thymus barrier

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The blood-thymus barrier protects the T lymphocytes that mature in the thymus from exposure to antigens . It is formed by different cell layers, including the continuation of the subcapsular epithelial layer of the thymus, which is in connection with the endothelium of the capillary . In the meantime the effectiveness of such a barrier has been questioned, since the blood vessels of the marrow are not enveloped. Here the matured T lymphocytes pass into the blood for removal .

Layer sequence of the blood-thymus barrier

The epithelial reticulum cells are located adjacent to the capsule of the thymus ; they form the first layer of the blood-thymus barrier . This surrounds the bark so that no foreign antigens can penetrate. The second layer is formed by the basement membrane of the reticulum cells. The following layers are formed by the wall parts of the capillary . The third layer is the perivascular connective tissue wall, the fourth layer is formed by the basement membrane of the capillary and the last and fifth layer consists of the endothelium of the capillary.

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