Bufotoxins

Parotid of Bufo alvarius

Bufotoxins are a group of chemically unrelated toxins produced by toads of the genus Bufo .

properties

Bufotoxine come in the parotid glands , the skin and the milky secretion before the toads. They serve to deter predators . The composition varies between species . The secreted poison contains, among other things, 5-MeO-DMT , bufadienolides such as bufagine , bufalin , bufotaline , bufothionine , and epinephrine , norepinephrine and serotonin .

Bufotoxine are sold by Bufo alvarius , Bufo americanus , Bufo arenarum , Bufo asper , blombergi Bufo , Bufo boreas , Bufo soplo , Bufo bufo gargarizans , Bufo formosus , Bufo fowleri , Bufo marinus , Bufo melanostictus , Bufo Peltocephalus , Bufo quercicus , Bufo regularis , Bufo valliceps , Bufo viridis and Bufo vulgaris .

history

A powder made from the skin of toads with bufotoxins was used in traditional Chinese medicine under the name chansu , 蟾酥, because of its content of bufadienolides with digitalis-like effects . The dried secretion was used ritually in voodoo .

Individual evidence

1. ^ Robert Alan Lewis: Lewis' Dictionary of Toxicology. CRC Press, 1998, ISBN 978-1-566-70223-2 , p. 198.
2. ↑ Steven B. Karch, MD: Karch's Pathology of Drug Abuse, Fourth Edition. CRC Press, 2008, ISBN 978-0-849-37881-2 , p. 354.
3. ↑ M. Hitt, DD Ettinger: Toad toxicity. In: The New England Journal of Medicine . Volume 314, Number 23, June 1986, pp. 1517-1518, PMID 3702971 .
4. ↑ ^{a b} D. Poudret: Les constituants toxiques des venins de crapaud et du Ch'an su (preparation issue de la médecine chinoise traditionnelle) . Thesis D. Pharm. Marseille. 1983, p. 145.
5. ↑ Poisindex. Toad toxins. Micromedex® Healthcare Series; v. 126 expires 1212005
6. ↑ Jean-Pierre Anger & Pascal Kintz; Bufoténine et bufoténidine: des alcaloïdes aux vertus hallucinogènes et aphrodisiaques extraits du venin de crapaud ; Revue Ann Toxicol Anal ; Volume 18, Number 1, 2006; Page (s) 55-64; doi : 10.1051 / ata: 2006029 ( PDF ).