CCL21

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CCL21
other names
  • Chemokine (CC Motif) ligand 21
  • SCYA21
  • SLC
  • Small Inducible Cytokine Subfamily A (Cys-Cys), Member 21
  • Efficient Chemoattractant For Lymphocytes
  • Secondary Lymphoid Tissue Chemokine
  • Beta chemokine Exodus-2
  • 6Ckine
  • CKb9
  • TCA4
  • ECL

Existing structural data : 2L4N

Properties of human protein
Mass / length primary structure 134 amino acids, 14646 Da
Identifier
External IDs
Orthologue
human House mouse
Entrez 6366 100862177
UniProt O00585 P86792
PubMed search 6366 100862177

CCL21 ( English CC chemokine ligand 21 ) is a cytokine belonging to the family of the C-C chemokines .

properties

CCL21 is involved in inflammatory processes. It has six instead of the usual four cysteines . CCL21 binds to the CCR7 receptor .

Individual evidence

  1. ↑ Hedrick JA, Zlotnik A: Identification and characterization of a novel beta chemokine containing six conserved cysteines . In: J. Immunol. . 159, No. 4, 1997, pp. 1589-93. PMID 9257816 .
  2. ↑ Yoshida R, Nagira M, Kitaura M, Imagawa N, Imai T, Yoshie O: Secondary lymphoid-tissue chemokine is a functional ligand for the CC chemokine receptor CCR7 . In: J. Biol. Chem. . 273, No. 12, 1998, pp. 7118-22. doi : 10.1074 / jbc.273.12.7118 . PMID 9507024 .