CCL23

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CCL23
other names
  • Chemokine (CC Motif) ligand 23
  • SCYA23
  • Small Inducible Cytokine Subfamily A (Cys-Cys), Member 23
  • Myeloid Progenitor Inhibitory Factor 1
  • Macrophage Inflammatory Protein 3
  • CK-BETA-8
  • MPIF-1
  • Ckb-8
  • MIP-3
  • C6 beta chemokines
  • Ckb-8-1
  • Hmrp-2a

Existing structural data : 1G91

Properties of human protein
Mass / length primary structure 120 amino acids, 13411 Da
Identifier
External IDs

CCL23 ( English CC chemokine ligand 23 ) is a cytokine belonging to the family of the C-C chemokines .

properties

CCL23 is involved in inflammatory processes. It is chemotactic for resting T cells and, to a lesser extent, neutrophils . CCL23 is produced in the lungs and liver and, to a lesser extent, in the bone marrow and placenta . It is induced by interleukin-4 .

Individual evidence

  1. ↑ Patel et al. Molecular and functional characterization of two novel human CC chemokines as inhibitors of two distinct classes of myeloid progenitors. J. Exp. Med. 185: 1163-1172, 1997.
  2. ^ H. Novak, A. Müller, N. Harrer, C. Günther, JM Carballido, M. Woisetschläger: CCL23 expression is induced by IL-4 in a STAT6-dependent fashion. In: Journal of Immunology (Baltimore, Md.: 1950). Volume 178, Number 7, April 2007, pp. 4335-4341, PMID 17371990 .