CCL25

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CCL25
other names
  • Chemokine (CC Motif) ligand 25
  • SCYA25
  • TECK
  • Small Inducible Cytokine Subfamily A (Cys-Cys), Member 25
  • Thymus Expressed Chemokine
  • Ck beta-15
Properties of human protein
Mass / length primary structure 150 amino acids, 16609 Da
Identifier
External IDs
Orthologue
human House mouse
Entrez 6370 20300
UniProt O15444 O35903
PubMed search 6370 20300

CCL25 ( English CC chemokine ligand 25 ) is a cytokine belonging to the family of the C-C chemokines .

properties

CCL25 is involved in inflammatory processes and in the development of T cells . CCL25 binds to the CCR9 receptor , which is produced by thymocytes , macrophages and dendritic cells .

Individual evidence

  1. ↑ AP Vicari, DJ Figueroa, JA Hedrick, JS Foster, KP Singh, S. Menon, NG Copeland, DJ Gilbert, NA Jenkins, KB Bacon, A. Zlotnik: TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development. In: Immunity. Volume 7, Number 2, August 1997, pp. 291-301, PMID 9285413 .
  2. ↑ A. Zaballos, J. Gutierrez, R. Varona, C. Ardavín, G. Márquez: Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. In: Journal of Immunology (Baltimore, Md.: 1950). Vol. 162, Number 10, May 1999, pp. 5671-5675, PMID 10229797 .
  3. ↑ Gosling et al., Cutting edge: identification of a novel chemokine receptor that binds dendritic cell and T cell active chemokines including ELC, SLC, and TECK. J Immunol. 2000, 164: 2851-6.