CCL26

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CCL26
other names
  • Chemokine (CC Motif) ligand 26
  • Macrophage Inflammatory Protein 4-Alpha
  • Thymic Stroma Chemokine-1
  • CC Chemokine IMAC
  • Eotaxin-3
  • SCYA26
  • Small Inducible Cytokine Subfamily A (Cys-Cys), Member 26
  • Chemokine N1
  • MIP-4 alpha
  • TSC-1
  • IMAC

Existing structural data : 1G2S , 1G2T

Properties of human protein
Mass / length primary structure 94 amino acids, 10648 Da
Identifier
External IDs

CCL26 ( English CC chemokine ligand 26 ) is a cytokine belonging to the family of the C-C chemokines .

properties

CCL26 is involved in inflammatory processes. It is produced in the heart , lungs , ovaries and in interleukin-4 -stimulated endothelial cells . CCL26 binds to the CCR3 receptor on eosinophils and basophils .

Individual evidence

  1. ↑ Shinkai et al. A novel human CC chemokine, eotaxin-3, which is expressed in IL-4-stimulated vascular endothelial cells, exhibits potent activity toward eosinophils. J. Immunol. 163: 1602-1610,1999.
  2. ↑ Guo et al. Molecular cloning and characterization of a novel human CC chemokine, SCYA26. Genomics 58: 313-317, 1999.
  3. ↑ Kitaura et al. Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3. J. Biol. Chem. 274: 27975-27980, 1999.