Complement receptor 2
| Complement receptor type 2 | ||
|---|---|---|
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| according to PDB 1GHQ | ||
| other names |
Complement C3d receptor, CD21, Epstein-Barr virus receptor, EBV receptor |
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| Properties of human protein | ||
| Mass / length primary structure | 1,033 amino acids , 112,916 Da | |
| Identifier | ||
| External IDs | ||
Complement receptor 2 (synonymous CD21 ) is a surface protein .
properties
CD21 is the receptor of C3Dd in the complement system . It is involved in the transport of immune complexes . CD21 is produced by B lymphocytes , T lymphocytes , pharyngeal epithelial cells , astrocytes and follicular dendritic cells of the spleen . The Epstein-Barr virus uses the complement receptor 2 for cell entry. CD21 is glycosylated .
Web links
Individual evidence
- ^ AC Jacobson, JH Weis: Comparative functional evolution of human and mouse CR1 and CR2. In: Journal of Immunology (Baltimore, Md.: 1950). Volume 181, Number 5, September 2008, pp. 2953-2959, PMID 18713965 , PMC 3366432 (free full text).