CD66e

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Carcinoembryonic antigen-related cell adhesion molecule 5
other names

Carcinoembryonic antigen, CEA, CD66e

Existing structure data : PDB  1E07 , PDB  2QSQ , PDB  2QST

Properties of human protein
Mass / length primary structure 702 amino acids , 76,795 Da
Identifier
External IDs
Orthologue (human)
Entrez 1048
Ensemble ENSG00000105388
UniProt P06731
Refseq (mRNA) NM_001291484.2
Refseq (protein) NP_001278413.1
PubMed search 1048

Carcinoembryonic antigen-related cell adhesion molecule 5 (synonym CEACAM5 , CD66e ) is a surface protein and cell adhesion molecule from the immunoglobulin superfamily .

properties

CD66e is one of twelve representatives of CEACAM. It is in adenocarcinomas of the epithelial cells of the digestive tract and in adenocarcinomas of fetal colon cells formed. CD66e forms homodimers , is glycosylated and has a GPI anchor .

The adhesins of the type Escherichia coli Dr bind to CD66e.

Web links

Individual evidence

  1. N. Beauchemin, A. Arabzadeh: Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis. In: Cancer metastasis reviews. Volume 32, Number 3-4, December 2013, pp. 643-671, doi : 10.1007 / s10555-013-9444-6 , PMID 23903773 .