CD66b

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Carcinoembryonic antigen-related cell adhesion molecule 8
other names

CD66b antigen, CD67 antigen, Carcinoembryonic antigen CGM6, Non-specific cross-reacting antigen NCA-95

Existing structural data : PDB  2DKS , PDB  4WTZ , PDB  4Y88

Properties of human protein
Mass / length primary structure 349 amino acids , 38,154 Da
Identifier
External IDs
Orthologue (human)
Entrez 1088
Ensemble ENSG00000124469
UniProt P31997
Refseq (mRNA) NM_001816.3
Refseq (protein) NP_001807.2
PubMed search 1088

Carcinoembryonic antigen-related cell adhesion molecule 8 (synonym CEACAM8 , CD66b ) is a surface protein and cell adhesion molecule from the immunoglobulin superfamily .

properties

CD66b is one of twelve representatives of CEACAM. It is produced by hematopoietic cells of the bone marrow and in chronic myeloid leukemia . CD66b is glycosylated and has a GPI anchor .

Web links

Individual evidence

  1. N. Beauchemin, A. Arabzadeh: Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis. In: Cancer metastasis reviews. Volume 32, Number 3-4, December 2013, pp. 643-671, doi : 10.1007 / s10555-013-9444-6 , PMID 23903773 .