Carbazole alkaloids

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Carbazole, basic structure of the carbazole alkaloids
Foliage leaves and fruits of Ochrosia elliptica
Fruits of Glycosmis pentaphylla

The carbazole alkaloids are natural substances of the indole alkaloid type, which can be derived from carbazole .

Occurrence

Carbazole alkaloids with intact benzene rings are rare. Olivacin was found in the bark of Aspidosperma olivaceum and ellipticin in Ochrosia elliptica . Some carbazole alkaloids, particularly Glybomin B, have been isolated from Glycosmis pentaphylla .

Representative

The representatives include a. Glycozolin , Olivacin and ellipticine and continue Glybomin B .

  • Glycozoline

  • Olivacin

  • Ellipticine

  • Glybomin B

properties

Carbazole alkaloids have cytotoxic and antifungal properties. Furthermore, they have a damaging effect on HIV viruses and tumor cells. Olivacin has fluorescent properties.

Individual evidence

  1. ↑ Entry on carbazole alkaloids. In: Römpp Online . Georg Thieme Verlag, accessed on May 31, 2020.
  2. ↑ a b c E. Breitmaier: Alkaloids . Springer Fachmedien, Wiesbaden 1997, ISBN 978-3-519-03542-8 , pp. 49 .
  3. ↑ a b c G. Yang, Y. Wu, Y. Chen: Alkaloids from the Stems of Glycosmis pentaphylla . In: Helvetica Chimica Acta . tape 95 , no. 8 , 2012, p. 1449-1454 , doi : 10.1002 / hlca.201200027 .

Web links

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