Carboxylic acid hydrazides

In chemistry, carboxylic acid hydrazides are a class of organic compounds and can be referred to as hydrazine derivatives of carboxylic acids with the general structure R-CO-NR ¹ -NR ² R ³ , where R ¹ , R ² and R ^{3 can be} organic radicals or hydrogen. The simplest representative is formhydrazide H-CO-NH-NH ₂ .

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  General structural formula of the carboxylic acid hydrazides

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  Formyl hydrazide, a derivative of formic acid

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  Acetyl hydrazide , a derivative of acetic acid

presentation

Carboxylic acid hydrazides can be z. B. by reacting carboxylic acid halides with hydrazine or correspondingly substituted hydrazines or by reducing N -nitroso-carboxamides.

properties

Carboxylic acid hydrazides are stable, polar solids and in some cases pharmacologically active. They also serve as synthesis intermediates, e.g. B. in the synthesis of nitrogen heterocycles and carboxylic acid azides .

Individual evidence

1. ^ Siegfried Hauptmann : Organic Chemistry , 2nd Edition, VEB Deutscher Verlag für Grundstoffindindustrie, Leipzig, 1985, p. 425, ISBN 3-342-00280-8 .
2. ^ Siegfried Hauptmann : Organic Chemistry , 2nd Edition, VEB Deutscher Verlag für Grundstoffindindustrie, Leipzig, 1985, p. 426, ISBN 3-342-00280-8 .