Cullen sign
The Cullen's sign (English: Cullen's sign ), as well as the Gray Turner's sign , a clinical sign of a serious acute pancreatitis . In the process, bluish-greenish spots appear periumbilically, i.e. around the navel. They are caused by edematous impregnation of the subcutis and local bleeding from small vessels, also known as ecchymoses , which are triggered by a local stimulus from pancreatic enzymes. In pancreatitis, the sign is considered to be unfavorable prognostically .
The sign is named after the Canadian gynecologist Thomas Stephen Cullen (1868–1953), who observed the occurrence of ruptured ectopic pregnancy .
literature
- Thomas Stephen Cullen : Embryology, anatomy, and diseases of the umbilicus together with diseases of the urachus. Saunders, Philadelphia PA et al. 1916, ( digitized ).
- Heiko Lübbers, Reiner Mahlke, Paul Georg Lankisch : Acute pancreatitis: what really matters in diagnostics and therapy. In: Medical Clinic. Vol. 102, No. 9, ISSN 0723-5003 , pp. 746-758, doi : 10.1007 / s00063-007-1093-5 .
- Alan P. Dickson, Clement W. Imrie: The incidence and prognosis of body wall ecchymosis in acute pancreatitis. In: Surgery, Gynecology & Obstetrics . Vol. 159, 1984, ISSN 0039-6087 , pp. 343-347.
