Cycloplegica

Cycloplegica are drugs that paralyze the ciliary muscle in the eye that is required for accommodation and thus lead to cycloplegia . They are often used in ophthalmological refraction determination and ensure that the measurements of the optical conditions are not falsified by involuntary accommodation of the test subject . They are also used in pleoptic treatments (penalization) of strabismus patients .

Cycloplegica usually also have a pupil-expanding effect . Cycloplegics generally act as blockers of the muscarinic acetylcholine receptors . Typical active ingredients are atropine , cyclopentolate , scopolamine and tropicamide . The effect of cycloplegic drugs decreases as soon as the active ingredients are broken down or sufficiently diluted by the metabolic processes of the muscle cells. Some Cycloplegica can work for several days, but preparations are usually used for eye examinations, the effect of which wears off after a few hours. The glare from the wide open pupil and the blurred vision from the paralyzed ciliary muscles represent a considerable risk in traffic and everyday life. Strong sunglasses with a high UV filter and accompanying people on the way home are therefore recommended.

literature

• Laurence L. Brunton (Eds.): Goodman & Gilman's The Pharmacological Basis of Therapeutics. 11th edition. McGraw-Hill, New York NY et al. 2006, ISBN 0-07-142280-3 .

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