Cyclopentolate

Structural formula
1: 1 mixture of ( R ) -form (top) and ( S ) -form (bottom)
General
Surname	Cyclopentolate
other names	( RS ) -2-dimethylaminoethyl-1-hydroxy-α-phenylcyclopentane acetate
Molecular formula	C 17 H 25 NO 3
External identifiers / databases
CAS number 512-15-2 5870-29-1 ( hydrochloride ) EC number 208-136-4 ECHA InfoCard 100.007.398 PubChem 2905 ChemSpider 2802 DrugBank DB00979 Wikidata Q867332
Drug information
ATC code	S01 FA04
properties
Molar mass	327.85 g mol −1
Physical state	firmly
safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed GHS labeling of hazardous substances Hydrochloride no GHS pictograms H and P phrases H: no H-phrases P: no P-phrases
Toxicological data	> 4000 mg kg −1 ( LD 50 ,  rat ,  oral ) 960 mg kg −1 ( LD 50 ,  mouse ,  oral )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Cyclopentolate is an anticholinergic agent from the group of mydriatics , which is used in ophthalmology in the form of eye drops to dilate the pupil and to paralyze accommodation . It is a racemate and a derivative of atropine that is used for the same areas of application. The effects occur more quickly than with atropine and last between 6 and 24 hours, also shorter than with atropine.

In pharmaceuticals, cyclopentolate is used as ( RS ) -cyclopentolate hydrochloride [( RS ) -cyclopentolate · HCl], i.e. as a racemate , it is a white, crystalline powder.

Individual evidence

1. ↑ ^{a b c d} Datasheet Cyclopentolate hydrochloride, analytical standard from Sigma-Aldrich , accessed on October 22, 2016 ( PDF ).
2. ^ European Pharmacopoeia , Deutscher Apotheker Verlag Stuttgart, 6th edition, 2008, pp. 2225–2226, ISBN 978-3-7692-3962-1 .