Disposition (medicine)

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As disposition (from the Latin dispositio borrowed , originally for "assembly"), or predisposition to disease , and predisposition called, is called an acquired or caused by external influences increased susceptibility to the development of diseases.

Under predisposition , genetic predisposition or genetic predisposition a is genetically predisposition for forming understood diseases. A disposition to disease of certain organs or organ systems is called diathesis . The term diathesis is - with regard to the delimitation from the term constitution - synonymous with disposition in the broader sense. In a narrower sense, disposition only refers to properties that are not determined by genetic factors, i.e., acquired through life history. This differentiation and stricter demarcation is essential , for example, for the psychotherapeutically influenceable factors of an illness. Disposition in the narrower sense is only related to peristatic factors.

Genetic disposition

A genetic predisposition ( hereditary predisposition ) refers to the from the structure or composition of genetic certain extraordinary predisposition of individuals or members of a family (= family history ), certain characteristics and diseases to inherit and develop the system-related susceptibility to certain diseases. A disease that only affects certain animal groups, species or races is usually caused by genetic differences.

Well-known examples of genetic predisposition are systemic lupus erythematosus , juvenile rheumatoid arthritis , periodontitis, and Alzheimer's disease . Various genotype variants are known here, which lead to an increased risk of the occurrence of the disease.

Sexual disposition

It is a gender or sexual disposition when the condition is more common in male or female individuals. Corresponding considerations are made in epidemiology and psychopathology .

Acquired disposition

An acquired disposition is caused by longer or more intensive contact with a disease-causing substance or pathogen or with stressors (incorrect loads). Occupational diseases and allergies fall into this group .

Web links

Wiktionary: Disposition  - explanations of meanings, word origins, synonyms, translations

Individual evidence

  1. a b Disposition - DocCheck Flexikon , 2019; u. a. also with "disposition" (as well as predisposition ) and also "Both terms are often used synonymously in medical colloquial language."
  2. a b Disposition - Duden , 2019; ibid under "origin" with "arrangement" and (under the meaning there, in the medical sense described here ) also with "disposition or susceptibility of the organism to certain diseases"
  3. Karl Wurm, AM Walter: Infectious Diseases. In: Ludwig Heilmeyer (ed.): Textbook of internal medicine. Springer-Verlag, Berlin / Göttingen / Heidelberg 1955; 2nd edition ibid. 1961, pp. 9–223, here: p. 22 ("Disease disposition is understood to be an increased susceptibility caused by external influences .")
  4. ^ Thure von Uexküll : Basic questions of psychosomatic medicine. Rowohlt Taschenbuch, Reinbek bei Hamburg 1963,
    Part I. The position of psychosomatic medicine in medicine. Cape. 8. Hereditary material and life history. as well as chapter 9. Disposing and triggering factors. P. 32 ff .;
    Part II. Dealing with the new task. Cape. 1. Psychiatry and psychosomatic medicine. P. 45, chap. 3 disposition, personality profile and willingness to be ill. P. 49; further positions: p. 57 f. (specific conflict according to Alexander ), as well as p. 64, 67 (social factors), p. 218 (medical sociology).