E2F
| E2F1 | ||
|---|---|---|
| other names |
E2F transcription factor 1; Retinoblastoma Associated Protein 1; Retinoblastoma binding protein 3; PRB binding protein E2F-1; RBAP-1; RBBP-3; RBBP3; E2F-1; PBR3; Transcription factor E2F1; RBAP1; RBP3 |
|
| Properties of human protein | ||
| Mass / length primary structure | 437 amino acids, 46920 Da | |
| Identifier | ||
| External IDs | ||
| Orthologue | ||
| human | House mouse | |
| Entrez | 1869 | 13555 |
| UniProt | Q01094 | Q61501 |
| Refseq (mRNA) | NM_005225 | |
| Refseq (protein) | NP_005216 | |
| Gene locus | Chr 20: 33.68 - 33.69 Mb | |
| PubMed search | 1869 |
13555
|
E2F is a family of transcription factors in eukaryotes . Three members of the family activate the transcription of genes (E2F1, 2 and E2F3a), six inhibit transcription (E2F3b, E2F4-8).
literature
- Jeremy M. Berg, John L. Tymoczko, Lubert Stryer : Biochemistry. 6th edition, Spektrum Akademischer Verlag, Heidelberg 2007, ISBN 978-3-8274-1800-5 .
- Donald Voet, Judith G. Voet: Biochemistry. 3. Edition. John Wiley & Sons, New York 2004, ISBN 0-471-19350-X .
- Bruce Alberts , Alexander Johnson, Peter Walter, Julian Lewis, Martin Raff, Keith Roberts: Molecular Biology of the Cell. 5th edition. Taylor & Francis, 2007, ISBN 978-0-8153-4106-2 .
Individual evidence
- ↑ C. Schaal, S. Pillai, SP Chellappan: The Rb-E2F transcriptional regulatory pathway in tumor angiogenesis and metastasis. In: Adv Cancer Res. Volume 121, 2014, pp. 147-182. doi: 10.1016 / B978-0-12-800249-0.00004-4 . PMID 24889531 .