Emperipolesis

Photomicrograph of Emperipoleses in Rosai-Dorfman disease . HE staining .

As emperipolesis or Emperipolese the receptacle or enclosure is, for example, lymphocytic cells referred to by other cells. In contrast to phagocytosis , the enveloped cells remain intact. In normal bone marrow, emperipoleses can occur in megakaryocytes , which can embrace other precursor cells of blood formation .

pathology

In Rosai-Dorfman disease , a rare disease from the group of histiocytoses , the occurrence of emperipoleses is characteristic: histologically , intact inflammatory cells can be detected in large histiocytes .

However, emperipoleses can also occur in other diseases: for example, in inflammation of the liver, emperipoleses can occur with intact lymphocytes in hepatocytes , including autoimmune hepatitis . Neutrophils and leukocytes can migrate through endothelial cells (transcellular migration, similar to leukodiapedesis ).

• 

  Neutrophil granulocyte in a megakaryocyte

• 

  Emperipolesis in Rosai-Dorfman disease

• 

  Neutrophil granulocyte in a megakaryocyte

See also

• Leukodiapedesis
• Pseudo-temperipolesis

Web links

• Emperipoleses in Rosai-Dorfman disease in the image database of the Institute for Pathology at the University of Basel .

Individual evidence

1. ^ Bain, Clark, Lampert: Bone marrow pathology. Blackwell Publishers, 2001 ISBN 0-632-05578-2 Full text on Google Books .
2. ↑ Rosai, Dorfman: Sinus histiocytosis with massive lymphadenopathy. A newly recognized benign clinicopathological entity. In: Arch Pathol. , 1969; 87 (1), pp. 63-70, PMID 5782438 .
3. ^ Dienes: Hepatitis . In: Pathology of the liver and biliary tract. Springer Verlag, Berlin 2000, ISBN 3-540-65501-8 , full text on Google Books.