Eradication

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Poliovirus infections internationally
year estimate Recorded
1975 - 49.293
1980 400,000 52,552
1985 - 38,637
1988 350,000 35,251
1990 - 23,484
1993 100,000 10,487
1995 - 07,035
2000 - [0] 02,971
2005 - 01,998
2010 - 01,352
2011 - 00.650
2012 - 00.222
2013 - 00.385
2014 - 00.359
2015 - 00.074
2016 - 00.037
2017 - 00.022nd
2018 - 00.033
2019 - 00.0174

Eradication (from Latin eradicare , 'to tear out with the root, to eradicate, to wipe out, to make it disappear completely, to cure from the ground up'; from ex "out" and radix "root"), also called germ elimination , means complete elimination in medicine a pathogen from the body or from a population .

individual

Many pathogens are destroyed by the healthy and immune-competent body sooner or later, but some are able to survive in certain niches. One speaks of persistence . Examples of this are herpes simplex viruses in ganglia of the autonomic nervous system , plasmodia in liver and blood cells and HIV in lymphocytes .

The pharmacological eradication of some of these persistent pathogens can be achieved with antibiotics or chemotherapeutic agents , for example the removal of Helicobacter pylori , the causative agent of many gastric ulcers, with a specific triple therapy. Some germs cannot be eradicated nowadays, this applies to the HI virus , for example .

population

Eradication is also used in connection with the targeted eradication of pathogens from a population ( e.g. polio eradication ). Pathogens that have been eradicated are the smallpox virus and the causative agent of rinderpest . Ongoing eradication programs for infectious diseases include the poliovirus , Dracunculus medinensis , Treponema pertenue and the causative agent of malaria . For this, u. a. Vaccinations carried out in the population.

See also

Individual evidence

  1. Lisa Mastny: Eradicating Polio: A Model for International Cooperation . Worldwatch Institute. January 25, 1999. Retrieved February 2, 2007.
  2. ^ PolioPlus Milestones . Rotary International. Archived from the original on March 3, 2007. Retrieved February 22, 2007.
  3. Wild Poliovirus Weekly Update . Global Polio Eradication Initiative. Retrieved March 17, 2010.
  4. WHO Vaccine Preventable Diseases: Monitoring system (PDF) World Health Organization. 2006. Archived from the original on February 11, 2007. Retrieved on February 2, 2007.
  5. Jong Wook Lee: Ending polio - now or never? . In: The Progress of Nations . UNICEF. 1995. Archived from the original on March 4, 2016. Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. Retrieved February 2, 2007. @1@ 2Template: Webachiv / IABot / www.unicef.org
  6. Wild Poliovirus 2008-2013 . Global Polio Eradication Initiative. Archived from the original on May 18, 2013. Retrieved February 9, 2013.
  7. http://www.polioeradication.org/dataandmonitoring/poliothisweek.aspx
  8. Due to the large increase in the number of vaccinators and field workers since 1998, the number of estimated cases is thought to be reasonably close to the actual reported number of cases in recent years. Aylward, Bruce, Jennifer Linkins: Polio Eradication: mobilizing and managing the human resources . World Health Organization. Retrieved February 1, 2007.