Feline Cushing Syndrome

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The Feline Cushing's syndrome (syn. Hyperadrenocorticism the cat ) is a disease in domestic cats , which is by the overactive adrenal glands to increased secretion of cortisol comes. In 90% of cases, the cause lies in the pituitary gland, as in Cushing's disease in humans, the remaining 10% are primarily diseases of one of the two adrenal glands.

Clinical picture, diagnosis and treatment

The most common symptoms in affected cats are changes in the skin (thin skin, hair loss , ulcers , pyoderma ), increased drinking ( polydipsia ), increased urination ( polyuria ), voraciousness ( polyphagia ), increase in abdominal girth, muscle loss, fatigue and weight loss.

The disease is often associated with unregulated diabetes , which is associated with hyperglycaemia .

A low-dose dexamethasone suppression test with 0.1 mg dexamethasone per kg body mass is carried out to confirm the diagnosis .

The best treatment results are achieved with Trilostan .

literature

  • SY Valentin, CC Cortright, RW Nelson, BM Pressler, D. Rosenberg, GE Moore, JC Scott-Moncrieff: Clinical Findings, Diagnostic Test Results, and Treatment Outcome in Cats with Spontaneous Hyperadrenocorticism: 30 Cases . In: Journal of Veterinary Internal Medicine . tape 28 , no. 2 , 2014, p. 481-487 , doi : 10.1111 / jvim.12298 , PMC 4858028 (free full text).