Fungicide resistance

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Fungicide resistance describes the property of microorganisms such as B. fungi to be immune or resistant to the action of fungicides .

consequences

Fungi are increasingly developing fungicide resistance, which has consequences for human medicine , agriculture and the food industry that are difficult to calculate worldwide. Mildew z. B. is a dreaded plant pest , Candida albicans settles on human tissue, the globally widespread, breathable mold Aspergillus fumigatus can cause fatal pneumonia in immunocompromised people ( death rate approx. 50%, → aspergillosis ). So far, this has usually been combated using fungicide- azole (→ fluconazole ), which is becoming increasingly difficult worldwide.

“Fungal infections in humans are responsible for more deaths than malaria or breast cancer . The numbers are comparable to those of tuberculosis or HIV . But that is a barely perceived problem. "

Counter-strategies

In the field of human medicine, eleven new corresponding active ingredients are currently (mid-2018) in phases one and two clinical studies .

In agriculture, new approaches such as B. genetic engineering measures are required in plant breeding because so far only two variants of known fungicides are in development.

See also

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