Cave cell

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A Höhl cell (also Höhlzelle written by Erwin Höhl ; engl also. Hoehl cell ) is a bipolar cell in the human tooth .

The Höhl cells are located in the peripheral part of the tooth pulp in a cell-rich subodontoblastic zone (Höhl cell layer), i.e. between the row of odontoblasts and the (low-nucleus) Weil zone . With their spindle-shaped longitudinal axis, they are aligned parallel to the odontoblasts .

Cavity cells are of mesenchymal origin and are described in the literature e.g. Sometimes also referred to as pre-odontoblasts or progenitor cells or mostly only as fibroblasts , but this is probably not applicable due to their ultrastructure, their metabolism and their embryological origin. The composition of the cell organelles corresponds to that of the odontoblasts, except that a bipolar arrangement predominates.

Höhl cells most likely form Korff fibers and argyrophilic (reticular) fibers and support odontoblast metabolism . During the formation of the pulp, pre-odontoblasts divide in the last mitosis into an odontoblast and a daughter cell, which migrates into the cavity cell layer of the pulp. In the event of injury or destruction of the primary odontoblast, these cavity cells may have the potential to differentiate into odontoblast-like cells and form repair dentin .

literature

  • LJ Baume: The biology of pulp and dentine. A historic, terminologic-taxonomic, histologic-biochemical, embryonic and clinical survey. Karger, Basel 1980.
  • M. Goldberg, N. Six, F. Decup, D. Buch, E. Soheili Majd, JJ. Lasfargues, E. Salih, L. Stanislawski L (2001): Application of bioactive molecules in pulp-capping situations. In: Adv Dent Res. 15, 2001, pp. 91-95.
  • M. Goldberg, N. Six, F. Decup, JJ. Lasfargues, E. Salih, K. Tompkins, A. Veis: Bioactive molecules and the future of pulp therapy. In: Am J Dent. 16, 2003, pp. 66-76.
  • M. Goldberg, AJ Smith: Cells and extracellular matrices of dentin and pulp: a biological basis for repair and tissue engineering. In: Crit Rev Oral Biol Med. 15, 2004, pp. 13-27.
  • E. Höhl: Contribution to the histology of the pulp and dentine. In: Arch Anat Physiol. 32, 1896, pp. 31-54.
  • SJ Jones, A. Boyde: Ultrastructure of dentin and dentinogenesis. In: A. Linde (Ed.): Dentin and dentinogenesis. Vol. I. CRC Press, Boca Raton 1984, pp. 81-134.