Heterotetramer

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The heterotetrameric molecule hemoglobin consists of four subunits of two different types ( colored red and blue ).

A heterotetramer is a protein that has four non- covalently linked protein subunits that are not all identical. A homotetramer , however, contains four identical subunits. Both are tetramers .

Examples would be hemoglobin ( see picture ), NMDA receptor , some aquaporins , AMPA receptors and some enzymes .

Individual evidence

  1. ^ GO term: protein heterotetramerization . YeastGenome. Archived from the original on September 27, 2011. Retrieved on May 14, 2011.
  2. ^ GO term: protein homotetramerization . YeastGenome. Archived from the original on September 27, 2011. Retrieved on May 14, 2011.
  3. ↑ John D. Neely, Christensen, Birgitte M., Nielsen, Søren, Agre, Peter: Heterotetrameric Composition of Aquaporin-4 Water Channels . In: Biochemistry . 38, No. 34, August 1, 1999, pp. 11156-11163. doi : 10.1021 / bi990941s . PMID 10460172 .
  4. ↑ T.-H. Chang, Hsieh, F.-L., Ko, T.-P., Teng, K.-H., Liang, P.-H., Wang, AH-J .: Structure of a Heterotetrameric Geranyl Pyrophosphate Synthase from Mint (Mentha piperita) Reveals Intersubunit Regulation . In: THE PLANT CELL ONLINE . 22, No. 2, February 5, 2010, pp. 454-467. doi : 10.1105 / tpc.109.071738 .