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Hiersemann is the family name of the following people:
- Alexandra Hiersemann (* 1960), German lawyer and politician
- Anton Hiersemann (1891–1969), German publisher
- Fritz Hiersemann (1930–1996), German politician (SPD), member of the Berlin House of Representatives
- Karl-Heinz Hiersemann (1944–1998), German state politician (Bavaria) (SPD)
- Karl Wilhelm Hiersemann (1854–1928), German antiquarian and publisher
Hiersemann stands for:
- Anton Hiersemann Verlag , academic book publisher based in Stuttgart