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Holper is the family name of the following people:
- Barbara Holper (1452–1514), mother of Albrecht Dürer
- Franz Holper (1862–1935), German painter and architect
- Hieronymus Holper , German goldsmith in Nuremberg
- Johann Holper (* 1949), Austrian trade unionist
- Karl Holper (1919–1997), Austrian politician
- Wilhelm Holper (1929–1983), Austrian politician
