Human placental actogen
The Human placental lactogen ( HPL , English Human placental lactogen or Chorionic somatomammotropin hormone , CSH), also briefly lactogen (placenta) is a hormone that during pregnancy in the placenta is formed and the syncytiotrophoblast is excreted. In structure and function, it is similar to somatotropin , a growth hormone. It may play a role in stimulating milk production by the mammary glands.
The protein consists of 191 amino acids with two intramolecular disulfide bridges and has a molecular mass of 22,304 Da .
HPL modifies the mother's metabolism during pregnancy. HPL makes the maternal cells less sensitive to insulin , and as a result the maternal blood sugar level rises . This ensures the fetal supply.
See also
literature
- Lois Jovanovic, Genell J. Subak-Sharpe: Hormones. The medical manual for women. (Original edition: Hormones. The Woman's Answerbook. Atheneum, New York 1987) From the American by Margaret Auer, Kabel, Hamburg 1989, ISBN 3-8225-0100-X , pp. 48 and 379.
Web links
- Human placental actogen. In: Online Mendelian Inheritance in Man . (English)