Intracutaneous injection

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Skin anatomy. The skin is made up of three layers, starting with the outermost layer: the epidermis, the dermis, and the subcutis. The intracutaneous or intradermal injection is made into the dermis.

As intracutaneous injection (from latin intra =, in ' cutis = skin'; inicere infuse Abbr. I c, too.. Intracutaneously written) or intradermal injection refers to the injection of a liquid medicament into the dermis (dermis). The dermis is located below the epidermis and above the subcutis . Thus, intracutaneous injection must be differentiated from epicutaneous and subcutaneous injection.


The intracutaneous injection is mainly used for allergy tests and the tuberculin test ( Mendel-Mantoux test ), since there are more defense cells (especially dendritic cells ) in the dermis than in the subcutaneous and intramuscular area.

It enables the treatment of hyperhidrosis , in which botulinum toxin is initiated intracutaneously.

Intracutaneous injection is also used to place a wheal in neural therapy and mesotherapy .

Injection technique

After applying a disinfectant solution and allowing it to take effect for at least 30 seconds, a fine cannula is used to puncture the skin almost parallel to the surface of the skin. The formation of a wheal and the lightening of the skin at the injection site indicate a correct intracutaneous injection.

Lancets or vaccination pistols can also be used for intracutaneous vaccination .

See also

Needle-free injection

Individual evidence

  1. L50.8 autoreactive urticaria . In: P. Altmeyer's Encyclopedia of Dermatology ; accessed on November 12, 2018
  2. A. Detjen et al .: Immunological diagnosis of tuberculosis - γ-interferon test . In: Monthly Pediatric Medicine, 2006, 154, pp. 152–159.
  3. Rzany B. Bechera FG. Feise K. et al: Guideline "Definition and Therapy of Primary Hyperhidrosis". (PDF) AWMF Reg. No. 013/059, 11/2017, p. 11
  4. H. Barop: Neural therapy according to Hunneke . (PDF; 147 kB) Pocket Atlas. Haug Verlag, (2013), ISBN 3-8304-7742-2 .