James Reilly (disambiguation)
James Reilly or James O'Reilly is the name of the following people:
- James Reilly (born 1955), Irish politician
- James O'Reilly (1855–1934), Irish clergyman, Bishop of Fargo
- James Bernard Reilly (1845–1924), American politician
- James F. Reilly (* 1954), American astronaut
- James W. Reilly (1828–1905), American general and politician