Joachim Jose
Joachim Jose (born January 12, 1961 in Quiigart ) holds a chair for Pharmaceutical and Medicinal Chemistry at the Westphalian Wilhelms University of Münster and focuses primarily on research into the evolutionary development of active ingredients and biocatalysts through bacterial surface displays .
Life
Joachim Jose studied biology at Saarland University, Saarbrücken, and received his doctorate in 1994 with a thesis on the structure and reaction mechanism of bacterial ureases.
During his time as a post-doc in the group of Prof. Thomas F. Meyer at the Max Planck Institute for Biology in Tübingen, he was primarily involved in the discovery and description of a new family of secretion proteins, the car transporters. The name "Autotransporter" was first mentioned in its publication in 1995 together with F. Jähnig and TF Meyer.
From 1998 to 2003 he was a research assistant (C1) in the group of Prof. Rolf W. Hartmann, Pharmaceutical and Medicinal Chemistry at the University of Saarland, and completed his habilitation with his thesis on the evolutionary development of drugs and biocatalysts through bacterial surface expression.
In 2004 Joachim Jose accepted an offer from Heinrich Heine University Düsseldorf for a professorship (C3) in bioanalytics at the Institute for Pharmaceutical and Medicinal Chemistry, where he was appointed head of the institute in 2008. Since March 2011 he has been a professor (W3) at the Chair for Pharmaceutical and Medicinal Chemistry at the Westphalian Wilhelms University in Münster. His awards include the GDCh / DPhG Innovation Award in Medicinal Chemistry in 1998 and the SaarLB Science Prize in 2004. In 2009, he was also recognized as a corresponding member of the National Academy of Pharmacy in France.
Joachim Jose is co-founder of two start-up companies in the field of "Active substance screening and selection" ("Pharmacelsus", founded in 2000) and "Biocatalytic synthesis and evolutive drug design" ("Autodisplay Biotech", 2008).
His research focuses primarily on the application of "Autodisplay", a technology platform developed in his group based on the Autotransporter secretion mechanism. Current applications include the expression of human target enzymes for inhibitor tests, evolutionary drug development through library expression and HT screening, biocatalytic synthesis of drugs and building blocks, and the development of biosensors through membrane technologies. Joachim Jose is married and has one son.
Scientific awards
- 1998 Innovation Prize for Medicinal Chemistry, jointly awarded by GDCh and DPhG
- 2004 SaarLB Science Prize
- 2009 election as a corresponding member of the French National Academy of Pharmacy
- 2013 Medal from the Faculty of Biology and Pharmacy, Claude Bernard University , Lyon
Web links
- Joachim Jose on the website of the University of Münster
Individual evidence
- ↑ Kürschner's German Scholar Calendar Online . Retrieved May 2, 2014.
- ↑ J. Jose, F. Jähnig, TF Meyer: Common structural features of IgA1 protease-like outer membrane protein autotransporters. In: Molecular microbiology. Volume 18, Number 2, October 1995, pp. 378-380, PMID 8709857 .
- ↑ SaarLB Science Prize
| personal data | |
|---|---|
| SURNAME | Jose, Joachim |
| BRIEF DESCRIPTION | German chemist, professor of pharmaceutical and medicinal chemistry |
| DATE OF BIRTH | January 12, 1961 |
| PLACE OF BIRTH | Quiver |