Jonathan C. Cohen

from Wikipedia, the free encyclopedia

Jonathan C. Cohen is a nutritionist and internist at the Eugene McDermott Center for Human Growth and Development at the University of Texas Southwestern Medical Center in Dallas . He is best known for his work on the genetic factors that affect serum levels of lipoproteins and cholesterol .

Cohen received a Ph.D. from the University of Cape Town in 1989. and then went to the University of Texas Southwestern Medical Center as a postdoctoral fellow , where he has worked since. Here he runs a research laboratory together with the geneticist Helen Hobbs .

Cohen studies genetic disorders that predispose to common conditions like coronary artery disease and fatty liver . Together with his research partner, he identified genes that play an important role in the metabolism of fats , cholesterol and triglycerides , and contributed to the elucidation of the biological function of the proteins that are encoded by these genes. Cohen showed that loss-of-function mutations of PCSK9 result in reduced cholesterol levels and offer protection against coronary heart disease. Hobbs and Cohen also identified the first genetic cause of non-alcoholic fatty liver in humans.

2016 Cohen and Hobbs were the Passano Award of the Passano Foundation Award, a prestigious US science award, the carrier often later a Nobel Prize received.

Web links

personal data
SURNAME Cohen, Jonathan C.
ALTERNATIVE NAMES Cohen, Jonathan
BRIEF DESCRIPTION Nutritionist at the University of Texas Southwestern Medical Center
DATE OF BIRTH 20th century