Karl-Heinz Kogel

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Karl-Heinz Kogel (born January 8, 1956 in Aachen ) is a German biologist and professor of plant biotechnology and plant protection at the Justus Liebig University in Giessen .

biography

Kogel studied biology and social sciences at RWTH Aachen from 1975 to 1981 . In 1983 he conducted research at the Weizmann Institute for Science in Rechovot Israel. In 1986 he received his PhD in biology from RWTH Aachen University. Until 1988 he worked as a postdoc at the Max Planck Institute for Plant Breeding Research in Cologne. After several years of work in the field of biopatents, he took over as laboratory manager of a working group in the field of cereal diseases at RWTH Aachen University. In 1996 he completed his habilitation there in plant physiology. In the same year he accepted a professorship for plant protection and plant diseases from JLU Giessen. From 2000 to 2006 Kogel was a member of a senate commission of the German Research Foundation (DFG). He was the coordinator for several DFG-funded research groups in the field of biotechnology and genetic engineering with a focus on grain. Since 2014 he has also been head of the TransMIT center for innovative crop protection.

Research priorities

Kogel's focus is on work on fungal endophytes and their symbiosis with cereals, as well as their use in agriculture to combat plant diseases. Since 2013, Kogel has been researching the role of various RNA molecules such as double-stranded RNA (dsRNA) and small non-coding RNA (siRNA; miRNA) in the development of cereal diseases and in the fight against these diseases. In addition, Kogel worked in biosafety research on the impact of transgenic grain on the environment ( green genetic engineering ). He is a pioneer for sustainable plant production through the application of green genetic engineering and genome editing ( CRISPR / Cas method ) as a way of reducing the use of pesticides.

honors and awards

Publications

Web links

Individual evidence

  1. ↑ Karl-Heinz Kogel CV
  2. ↑ TransMIT center for innovative plant protection
  3. Jump up ↑ Waller F, Achatz B, Baltruschat H, Fodor J, Becker K, Fischer M, Heier T, Hückelhoven R, Neumann C, Franken P, Kogel KH (2005): The endophytic fungus Piriformospora indica reprograms barley to salt stress tolerance, disease resistance and higher yield . Proc. Nat. Acad. Sci. USA 102, 13386-13391. DOI: 10.1073 / pnas.0504423102
  4. ↑ Kogel KH, Franken P, Hückelhoven R (2006): Endophyte or parasite - what decides? Current Opinion in Plant Biology 9, 358-363. DOI: 10.1016 / j.pbi.2006.05.001
  5. ↑ Deshmukh S, Hückelhoven R, Schäfer P, Imani J, Sharma M, Weiß M, Waller F, Kogel KH (2006): The root endophytic fungus Piriformospora indica requires host cell death for proliferation during mutualistic symbiosis with barley. Proc. Nat. Acad. Sci USA 103, 18450-18457. DOI: 10.1073 / pnas.0605697103
  6. ↑ Zuccaro A, Lahrmann U, Güldener U, Langen G, Pfiffi S, Biedenkopf D, Samans B, Wong P, Grimm C, Basiewicz M, Murat C, Martin F, Kogel KH (2011): Endophytic life strategies decoded by genome and transcriptome analyzes of the mutualistic root symbiont Piriformospora indica. PLoS Pathogens 7 (10): e1002290. DOI: 10.1371 / journal.ppat.1002290
  7. ↑ Glaeser SP, Imani J, Alabid I, Guo H, Käufer P, Hardt M, Blom J, Goesmann A, Rothballer M, Hartmann A, Kogel KH (2015): Non-pathogenic Rhizobium radiobacter F4 deploys plant beneficial activity independent of its host Piriformospora indica . ISME 10 (4): 871-84; DOI: 10.1038 / ismej.2015.163 .
  8. ^ To Q, Ehlers K, Kogel KH, van Bel AJE, Hückelhoven R (2006a): Multivesicular compartments proliferate in susceptible barley and resistant MLA12-barley leaves in response to infection by the biotrophic barley powdery mildew fungus. New Phytologist, 172, 563-576. DOI: 10.1111 / j.1469-8137.2006.01844.x
  9. ↑ To Q, Hückelhoven R, Kogel KH, and van Bel AJE (2006b): Multivesicular Bodies Participate in Vesicle-Associated Resistance Response to Pathogen in Plants. Cellular Microbiology 8, 1009-1019. DOI: 10.1111 / j.1462-5822.2006.00683.x
  10. ↑ Koch A, Kumara N, Weber L, Keller L, Imani J, Kogel KH (2013): Host-induced gene silencing of cytochrome P450 lanosterol C14α-demethylase-encoding genes confers strong resistance to Fusarium species . Proc. Nat. Acad. Sci USA 110: 19324-19329. DOI: 10.1073 / pnas.1306373110
  11. ↑ Koch A, Biedenkopf D, Furch A, Weber L, Rossbach O, Abdellatef E, Linicus L, Johannsmeier J, Jelonek L, Goesmann A, Cardoza V, McMillan J, Mentzel T, Kogel KH (2016): An RNAi-based Control of Fusarium graminearum infections through spraying of long dsRNAs involves a plant passage and is controlled by the fungal silencing machinery . PLOS pathogens. DOI: 10.1371 / journal.ppat.1005901
  12. ↑ Cai Q, He B, Kogel KH, Jin H (2018): Cross-kingdom RNA trafficking and environmental RNAi - nature's blueprint for modern crop protection strategies. Curr Opin. Microbio. DOI: 10.1016 / j.mib.2018.02.003
  13. ↑ Kogel KH, Voll LM, Schäfer P, et al. (2010): Transcriptome and metabolome profiling of fieldgrown transgenic barley lack induced differences but show cultivar-specific variances . Proc. Nat. Acad. Sci USA 107: 6198-6203. DOI: 10.1073 / pnas.1001945107
  14. ↑ Kumar N, Galli M, Ordon J, Stuttmann J, Kogel KH, Imani: Further analysis of barley MORC1 using a highly efficient RNA-guided Cas9 gene editing system. Plant Biotechnology Journal DOI: 10.1111 / pbi.12924
  15. ↑ "Pioneering achievements" in phytomedicine , in: Gießener Anzeiger 2016
personal data
SURNAME Kogel, Karl-Heinz
BRIEF DESCRIPTION German plant biotechnologist
DATE OF BIRTH January 8, 1956
PLACE OF BIRTH Aachen