Kay Severin

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Kay Severin (* 1967 in Germany ) is a German chemist ( organic chemistry and organic synthesis, catalysis ).

Severin received his doctorate in 1995 with Wolfgang Beck at the Ludwig Maximilians University in Munich . As a post-doctoral student he was with M. Reza Ghadiri at the Scripps Research Institute and from 1997 had a research group at the University of Munich, where he completed his habilitation. In 2001 he became assistant professor and in 2009 professor at the École polytechnique fédérale de Lausanne . There he is in the supramolecular chemistry laboratory.

In 2001 he received the ADUC Prize, the Arnold Sommerfeld Prize of the Bavarian Academy of Sciences and the Heinz Maier Leibnitz Prize . In 2003 he received the Werner Prize from the Swiss Chemical Society and in 2005 the Otto Roelen Medal from DECHEMA . In 2008 he was Dalton Transactions European Lecturer. In 2007 he received the Chemistry Prize of the Academy of Sciences in Göttingen for important work in the field of organometallic synthesis and catalysis (laudation).

In 1996 he demonstrated Ghadiri for the first time, a self-reproducing peptide. It was an alpha-helix of 32 amino acids based on a domain of the yeast transcription factor GCN4.

Fonts (selection)

  • with DH Lee, AJ Kennan, MR Ghadiri: A synthetic peptide ligase, Nature, Volume 389, 1997, p. 706
  • with DH Lee, Y. Yokobayashi, MR Ghadiri: Emergence of symbiosis in peptide self-replication through a hypercyclic network, Nature, Volume 390, 1997, p. 591
  • with R. Bergs, W. Beck: Bioorganometallic Chemistry - Transition Metal Complexes with α-Amino Acids and Peptides, Angewandte Chemie Int. Ed., Vol. 37, 1998, pp. 1634-1654
  • Self-assembled organometallic receptors for small ions, Coordination Chemistry Reviews, Volume 245, 2003, pp. 3-10
  • with MG Mendoza-Ferri a. a .: Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity, Journal of Medicinal Chemistry, Volume 52, 2009, pp. 916-925
  • with S. Mirtschin u. a .: A coordination cage with an adaptable cavity size, J. Am. Chem. Soc., Vol. 132, 2010, pp. 14004-14005
  • with H. Piotrowski, K. Polborn, G. Hilt: A Self-Assembled Metallomacrocyclic Ionophore with High Affinity and Selectivity for Li + and Na +, J. Am. Chem. Soc, Vol. 123, 2001, pp. 2699-2700
  • The advantage of being virtual - Target-induced adaptation and selection in dynamic combinatorial libraries, Chemistry - A European Journal, Volume 10, 2004, pp. 2565-2580
  • with A. Buryak: A chemosensor array for the colorimetric identification of 20 natural amino acids, Journal of the American Chemical Society, Volume 127, 2005, pp. 3700-3701
  • with N. Christinat, R. Scopelliti: Multicomponent assembly of boronic acid based macrocycles and cages, Angewandte Chemie Int. Ed., Vol. 47, 2008, pp. 1848-1852

Web links

Individual evidence

  1. ^ DH Lee, JR Granja, JA Martinez, K. Severin, MR Ghadiri, A self-replicating peptide, Nature, Volume 382, ​​1996, p. 525.
personal data
SURNAME Severin, Kay
BRIEF DESCRIPTION German chemist
DATE OF BIRTH 1967