Cross resistance
A cross-resistance refers to the insensitivity of a bacterial species against two or more antibiotics , which are usually built very similar or identical mechanisms of action have. For example, penicillins and cephalosporins show such cross-resistance. Both have a similar chemical structure and interrupt the cell wall biosynthesis of bacteria by inhibiting enzymes that are responsible for the cross-linking of peptidoglycans .
Cross-resistance is also seen with antifungal drugs (drugs used to treat fungal infections ), e.g. B. Itraconazole and Fluconazole .
Under a parallel resistance is defined as the insensitivity to unrelated agents due to different mechanisms of resistance.