Lawrence H. Einhorn
Lawrence H. Einhorn (* 1942 in Dayton , Ohio ) is an American medical doctor ( oncologist ). He is known for the introduction of a combined chemotherapy against testicular cancer with cisplatin , which improved the survival rate in the 1970s dramatically.
Lawrence Einhorn graduated from Indiana University with a bachelor's degree in 1965 and received his MD in medicine from the University of Iowa in 1968 . He completed his internship and residency at Indiana University Medical Center . From 1969 to 1971 he served as a doctor at an air force base in Wichita during the Vietnam War . He continued his specialist training (fellowship) in hematology and oncology in 1971/72 at Indiana University and in Houston ( MD Anderson Hospital Tumor Institute with Emil J. Freireich ). He then went to Indiana University (Medical Center), where he became Assistant Professor in 1973 , Associate Professor in 1976 and Professor in 1979. In 1987 he became a Distinguished Professor .
In 1974 he carried out a phase II clinical study which demonstrated the extraordinary success of cisplatin in combination with bleomycin and vinblastine in testicular cancer. The then new component was cisplatin, Einhorn had already used the other preparations as chemotherapeutic agents against testicular cancer and another study had previously shown short-term remissions after treatment with cisplatin alone. While the healing rate was 5 to 10 percent before the therapy introduced by Einhorn, a remission rate of 70 percent was achieved with the new chemotherapy. He also found ways to minimize the side effects of cisplatin and continued to improve chemotherapy for testicular cancer, in particular, in the 1980s, vinblastine was replaced by etoposide , which had fewer side effects and a higher cure rate. In addition, the time required for chemotherapy could be significantly reduced.
Most recently, he has been working on making cisplatin a more successful chemotherapy drug in lung cancer.
He wrote over 300 scientific papers and 70 book chapters.
In 1992 he received the Kettering Prize . He also received the Richard and Hinda Rosenthal Foundation Award for Cancer Research from the American Association for Cancer Research in 1981 , the Distinguished Clinican Award from the Milken Foundation in 1989 , the David A. Karnofsky Memorial Award in 1990 , the ACCC Clinical Oncology Award in 1991 , and the Herman B. Wells Visionary Award , the State of Israel Peace Medal and the Vermeil Medal of the City of Paris , 2012 Joseph H. Burchenal Memorial Award from the American Association for Cancer Research . He received Indiana University's Presidential Medal of Honor in 1996 and its Teaching Excellence Award in 1998 . In 2000 he became President of the American Society of Clinical Oncology . He is a member of the National Academy of Sciences (2001), the American Philosophical Society and a Fellow of the American College of Physicians .
Web links
- William P. Didusch Center for Urology History
- How Einhorn Helped Turn a Deadly Cancer Into a Curable Disease, Onclife, May 28, 2014
Individual evidence
| personal data | |
|---|---|
| SURNAME | Einhorn, Lawrence H. |
| BRIEF DESCRIPTION | American medic (oncologist) |
| DATE OF BIRTH | 1942 |
| PLACE OF BIRTH | Dayton , Ohio |