Lozenge
As a lozenge or oral-transmucosal therapeutic system is defined as a medical substances containing tablet that orally ingested, but not swallowed, but the mouth is left and should be resolved there.
Lozenges are preferred when the active ingredient's area of action is in the oral and smoking area (e.g. local anesthetics and anti-inflammatory drugs), or when the active ingredient is to get into the bloodstream directly through the oral mucosa. The latter has two advantages: on the one hand, the drug gets into the bloodstream very quickly - on the other hand, the portal vein system of the liver can be bypassed (for drugs that are metabolized very quickly by the liver ). Another reason may be that with larger amounts of active ingredient, the tablet is too big to swallow and is therefore sucked or chewed.
The so-called lollipop is a special form . It consists of a lozenge that is glued to a plastic handle with an edible glue. In the therapy of acute tumor pain in patients with swallowing difficulties z. B. used a fentanyl-containing lollipop.
Individual evidence
- ↑ lozenge. In: DocCheck Flexikon. Retrieved January 4, 2018 .
- ↑ Martin Allwang: What you should know about tablets. In: Apothekenumschau. October 14, 2016, accessed January 4, 2018 .
- ↑ Annina Bergner: Modern dosage forms. Part 1: Lollipops as Medicines. ptaheute.de of November 15, 2018; accessed on December 10, 2019
