Macrocytosis
As macrocytosis (macros, Greek for large) is referred to in medicine, the occurrence of abnormally high red blood cells ( macrocytes ) extending according to a blood sampling in blood show and their mean corpuscular volume (MCV) in comparison with the normal case to more than 98 femto liter ( fl) is increased. If there is anemia at the same time, it is called macrocytic anemia .
Macrocytosis is observed among other things:
- during treatment of deficiency anemia ( regenerative ),
- for smokers,
- with liver cirrhosis ,
- in the case of alcoholism , up to four months after stopping alcohol consumption and
- with vitamin B 12 or folic acid deficiency.
Myeloproliferative diseases and feline leukemia can also be responsible for macrocytosis in animals . In puppies , macrocytosis is physiological in the first few days of life.
Macrocytosis can develop as an artifact in overaged or damaged specimens.
literature
- Gerhard Thews , Peter Vaupel : Vegetative Physiology. Springer-Verlag, 2013, ISBN 978-3-662-10747-8 , p. 39 ( limited preview in Google book search).
Individual evidence
- ↑ a b L. Thomas (Ed.): Labor und Diagnose . 5th edition (1998). S. 486. TH-Books-Verl.-Ges. Frankfurt / Main. ISBN 3-9805215-3-2 .
- ↑ a b R. Mitschke: Interpretation of changes in the blood smear - 2. Erythrocytes and thrombocytes. In: Fachpraxis 49 (2006), pp. 14-20.
