Miniature inverted-repeat transposable element

A miniature inverted-repeat transposable element (MITE, dt. 'Miniature-transposable element with repeating end sequences') is a transposable DNA element with inverted repeats .

properties

As transposable elements, MITE are a form of self-serving DNA and occur in archaea , bacteria, plants and animals. MITEs are not autonomously replicating as they presumably rely on the use of a transposase from other related transposons . At both ends of the double-stranded DNA sequence of a MITE, which is usually less than 500 base pairs long, there are repeating end sequences ( inverted repeats ) that originally enabled the MITE to be inserted at this point in the genome and enables the MITE to be recombined with other genomic regions. MITE occur more frequently in unfolded, transcription-active areas.

MITE are divided into different families based on their homology to transposons: PIF / Harbinger , Tc1 / mariner , PiggyBac , hAT , P element and Mutator .

literature

N. Jiang: Computational methods for identification of DNA transposons. In: Methods in molecular biology (Clifton, NJ). Volume 1057, 2013, ISSN 1940-6029 , pp. 289-304, doi : 10.1007 / 978-1-62703-568-2_21 , PMID 23918437 .

Individual evidence

↑ ^a ^b ^c I. Fattash, R. Rooke, A. Wong, C. Hui, T. Luu, P. Bhardwaj, G. Yang: Miniature inverted-repeat transposable elements: discovery, distribution, and activity. In: Genome / National Research Council Canada = Génome / Conseil national de recherches Canada. Volume 56, Number 9, September 2013, ISSN 1480-3321 , pp. 475-486, doi : 10.1139 / gen-2012-0174 , PMID 24168668 .
^ K. Brügger, P. Redder, Q. She, F. Confalonieri, Y. Zivanovic, RA Garrett: Mobile elements in archaeal genomes. In: FEMS microbiology letters. Volume 206, Number 2, January 2002, ISSN 0378-1097 , pp. 131-141, PMID 11814653 .
↑ N. Delihas: Small mobile sequences in bacteria display diverse structure / function motifs. In: Molecular microbiology. Volume 67, number 3, February 2008, ISSN 0950-382X , pp. 475-481, doi : 10.1111 / j.1365-2958.2007.06068.x , PMID 18086200 , PMC 2229807 (free full text).
↑ P. Sampath, J. Murukarthick, NK Izzah, J. Lee, HI Choi, K. Shirasawa, BS Choi, S. Liu, IS Nou, TJ Yang: Genome-wide comparative analysis of 20 miniature inverted-repeat transposable element families in Brassica rapa and B. oleracea. In: PloS one. Volume 9, number 4, 2014, p. E94499, ISSN 1932-6203 , doi : 10.1371 / journal.pone.0094499 , PMID 24747717 , PMC 3991616 (free full text).
^ GL Wallau, P. Capy, E. Loreto, A. Hua-Van: Genomic landscape and evolutionary dynamics of mariner transposable elements within the Drosophila genus. In: BMC genomics. Volume 15, 2014, ISSN 1471-2164 , p. 727, doi : 10.1186 / 1471-2164-15-727 , PMID 25163909 , PMC 4161770 (free full text).
↑ E. Satovic, M. Plohl: Tandem repeat-containing MITEs in the clam Donax trunculus. In: Genome biology and evolution. Volume 5, number 12, 2013, ISSN 1759-6653 , pp. 2549-2559, doi : 10.1093 / gbe / evt202 , PMID 24317975 , PMC 3879986 (free full text).
^ Q. Zhang, J. Arbuckle, SR Wessler: Recent, extensive, and preferential insertion of members of the miniature inverted-repeat transposable element family Heartbreaker into genic regions of maize. In: Proceedings of the National Academy of Sciences . Volume 97, Number 3, February 2000, ISSN 0027-8424 , pp. 1160-1165, PMID 10655501 , PMC 15555 (free full text).
^ C. Feschotte, N. Jiang, SR Wessler: Plant transposable elements: where genetics meets genomics. In: Nature Reviews Genetics . Volume 3, Number 5, May 2002, ISSN 1471-0056 , pp. 329-341, doi : 10.1038 / nrg793 , PMID 11988759 .
↑ C. Feschotte, X. Zhang, SR Wessler: Miniature inverted-repeat transposable elements (MITEs) and their relationship with established DNA transposons. In: Mobile DNA II. Edited by N. Craig, R. Craigie, M. Gellert, and A. Lambowitz. American Society of Microbiology Press, Washington, DC 2002, pp. 1147-1158.

[PMID_24168668-1] I. Fattash, R. Rooke, A. Wong, C. Hui, T. Luu, P. Bhardwaj, G. Yang: Miniature inverted-repeat transposable elements: discovery, distribution, and activity. In: Genome / National Research Council Canada = Génome / Conseil national de recherches Canada. Volume 56, Number 9, September 2013, ISSN 1480-3321 , pp. 475-486, doi : 10.1139 / gen-2012-0174 , PMID 24168668 .

[2] K. Brügger, P. Redder, Q. She, F. Confalonieri, Y. Zivanovic, RA Garrett: Mobile elements in archaeal genomes. In: FEMS microbiology letters. Volume 206, Number 2, January 2002, ISSN 0378-1097 , pp. 131-141, PMID 11814653 .

[3] N. Delihas: Small mobile sequences in bacteria display diverse structure / function motifs. In: Molecular microbiology. Volume 67, number 3, February 2008, ISSN 0950-382X , pp. 475-481, doi : 10.1111 / j.1365-2958.2007.06068.x , PMID 18086200 , PMC 2229807 (free full text).

[4] P. Sampath, J. Murukarthick, NK Izzah, J. Lee, HI Choi, K. Shirasawa, BS Choi, S. Liu, IS Nou, TJ Yang: Genome-wide comparative analysis of 20 miniature inverted-repeat transposable element families in Brassica rapa and B. oleracea. In: PloS one. Volume 9, number 4, 2014, p. E94499, ISSN 1932-6203 , doi : 10.1371 / journal.pone.0094499 , PMID 24747717 , PMC 3991616 (free full text).

[5] GL Wallau, P. Capy, E. Loreto, A. Hua-Van: Genomic landscape and evolutionary dynamics of mariner transposable elements within the Drosophila genus. In: BMC genomics. Volume 15, 2014, ISSN 1471-2164 , p. 727, doi : 10.1186 / 1471-2164-15-727 , PMID 25163909 , PMC 4161770 (free full text).

[6] E. Satovic, M. Plohl: Tandem repeat-containing MITEs in the clam Donax trunculus. In: Genome biology and evolution. Volume 5, number 12, 2013, ISSN 1759-6653 , pp. 2549-2559, doi : 10.1093 / gbe / evt202 , PMID 24317975 , PMC 3879986 (free full text).

[7] Q. Zhang, J. Arbuckle, SR Wessler: Recent, extensive, and preferential insertion of members of the miniature inverted-repeat transposable element family Heartbreaker into genic regions of maize. In: Proceedings of the National Academy of Sciences . Volume 97, Number 3, February 2000, ISSN 0027-8424 , pp. 1160-1165, PMID 10655501 , PMC 15555 (free full text).

[8] C. Feschotte, N. Jiang, SR Wessler: Plant transposable elements: where genetics meets genomics. In: Nature Reviews Genetics . Volume 3, Number 5, May 2002, ISSN 1471-0056 , pp. 329-341, doi : 10.1038 / nrg793 , PMID 11988759 .

[9] C. Feschotte, X. Zhang, SR Wessler: Miniature inverted-repeat transposable elements (MITEs) and their relationship with established DNA transposons. In: Mobile DNA II. Edited by N. Craig, R. Craigie, M. Gellert, and A. Lambowitz. American Society of Microbiology Press, Washington, DC 2002, pp. 1147-1158.