Muscle spasm-muscle pain and fasciculations syndrome

Classification according to ICD-10
R25.3	Fasciculation
M79.1	Myalgia
ICD-10 online (WHO version 2019)

The muscle spasms-muscle-pain-and-fasciculations-syndrome is a rare disease with the eponymous main characteristics muscle cramps , muscle pain and fasciculations . Usually strong muscle spasms and twitching exist in otherwise healthy people.

The disease is the mildest form of the hyperexcitability syndromes of the peripheral nerves .

Synonyms are: Crampus fasciculation syndrome; Fasciculatory myalgia syndrome; Convulsive fasciculation syndrome

The name was coined by the authors of the first description from 1991 by the neurologist A. J. Tahmoush and colleagues.

Clinical manifestations

Clinical criteria are:

Painful muscle spasms, often in the thighs and lower legs
Physical activity can be a trigger
Muscle stretching and / or massage can have a soothing effect.

A wide variety of muscle groups can be involved.

There is a high incidence of

therapy

Treatment with carbamazepine , gabapentin , lamotrigine or pregabalin has been helpful in individual cases.

literature

T. Liewluck, CJ Klein, LK Jones: Cramp-fasciculation syndrome in patients with and without neural autoantibodies. In: Muscle & nerve. Vol. 49, No. 3, March 2014, pp. 351-356, doi: 10.1002 / mus.23935 , PMID 23836298 .

Individual evidence

↑ ^a ^b ^c ^d Rare Diseases
↑ BA Kealani: Cramp Fasciculation Syndrome: A Peripheral Nerve Hyperexcitability Disorder. In: Pakistan Journal of Neurological Sciences. Vol. 9 No. 3, 2014 http://www.pkjns.com/wp-content/uploads/2014/12/7-artical.pdf
↑ AJ Tahmoush, RJ Alonso, GP Tahmoush, TD Heiman-Patterson: Cramp-fasciculation syndrome: a treatable hyperexcitable peripheral nerve disorder. In: Neurology. Vol. 41, No. 7, July 1991, pp. 1021-1024, PMID 1648679 .
^ S. Braune, M. Hentschel, FX Glocker, CH Lücking: Involvement of the esophagus in the cramp-fasciculation syndrome. In: Muscle & nerve. Vol. 21, No. 6, June 1998, pp. 802-804, PMID 9585337 .

[rare-1] Rare Diseases

[2] BA Kealani: Cramp Fasciculation Syndrome: A Peripheral Nerve Hyperexcitability Disorder. In: Pakistan Journal of Neurological Sciences. Vol. 9 No. 3, 2014 http://www.pkjns.com/wp-content/uploads/2014/12/7-artical.pdf

[3] AJ Tahmoush, RJ Alonso, GP Tahmoush, TD Heiman-Patterson: Cramp-fasciculation syndrome: a treatable hyperexcitable peripheral nerve disorder. In: Neurology. Vol. 41, No. 7, July 1991, pp. 1021-1024, PMID 1648679 .

[4] S. Braune, M. Hentschel, FX Glocker, CH Lücking: Involvement of the esophagus in the cramp-fasciculation syndrome. In: Muscle & nerve. Vol. 21, No. 6, June 1998, pp. 802-804, PMID 9585337 .