OSB
OSB is an abbreviation for:
- Grand Glaize-Osage Beach Airport , IATA code for a regional airport in Osage Beach, Missouri, USA
- Oberpfälzer Schützenbund e. V., an umbrella organization for sport shooting in the Upper Palatinate
- OEM for System Builder , Microsoft's OEM versions, see Original Equipment Manufacturer
- Oldenburger Schützenbund e. V., as a regional association umbrella organization of 185 shooting clubs in 16 districts
- Operational status bit , a term from computer science
- Oracle Service Bus , a technology from the software company Oracle
- Ordo Sancti Benedicti , Latin. for the Order of the Benedictines and Benedictine
- Ortenau-S-Bahn GmbH, a former railway company in the Ortenau district
- OSB board ( Oriented Strand Board ), also chipboard
