Otto Hesse (disambiguation)
Otto Hesse is the name of the following people:
- Otto Hesse (1811–1874), German mathematician
- Otto Hesse (District Administrator) (1821–1904), German District Administrator
- Otto Hesse (teacher) (1895 – after 1950), German teacher, genealogist and NS- hereditary and racial hygiene journalist
- Otto Ernst Hesse (1891–1946), German playwright and publicist
- Otto Justus Basilius Hesse († 1793), German clergyman