Parakeratosis

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As parakeratosis refers to a disorder of keratinization ( dyskeratosis ) formed by remaining of nuclei is characterized or nuclear residues in the stratum corneum. Often the horny layer thickens at the same time (parakeratotic hyperkeratosis ). Parakeratosis arises from the accelerated development of the keratinocytes or a disruption of the maturation of the keratinocytes .

Typical diseases associated with parakeratosis are psoriasis , eczema and Bowen's disease .

In dogs, distemper , inflammation, ectoparasite infestation, dermatophilosis , dermatophytosis , zinc deficiency , chronic arsenic and thallium poisoning and the hepatocutaneous syndrome can lead to parakeratosis. A genetic parakeratosis has been described in dogs and cattle. Zinc deficiency is particularly important in pigs.

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