Pfeiffer effect

The Pfeiffer effect describes a phenomenon in the stereochemistry of organic compounds. The name goes back to the German chemist Paul Pfeiffer (1875–1951).

If the solution of a labile racemate is added to the solution of a chiral compound , the optical activity changes . The racemic compounds are mainly metal complexes . A bond in the second coordination sphere (outer sphere) is assumed to be the mechanism.

literature

PE Schipper: Contributions to the Pfeiffer Effect . In: Inorganica Chimica Acta . tape 12 , no. 1 , 1975, p. 199-204 , doi : 10.1016 / S0020-1693 (00) 89860-6 .
S. Kirschner, N. Ahmad, C. Munir, RJ Pollock: The Pfeiffer effect, outer-sphere complexation, and the absolute configuration of dissymmetric coordination compounds . In: Pure and Applied Chemistry . tape 51 , no. 4 , 1979, p. 913-923 , doi : 10.1351 / pac197951040913 .
RD Gillard, PA Williams: Origins of the Pfeiffer effect . In: International Reviews in Physical Chemistry . tape 5 , no. 2-3 , 1986, pp. 301-305 , doi : 10.1080 / 01442358609353395 .

Individual evidence

↑ P. Pfeiffer, K. Quehl: About a new effect in solutions of optically active substances (I. Commun.) . In: Reports of the German Chemical Society . tape 64 , no. 10 , 1931, p. 2667–2671 , doi : 10.1002 / cber.19310641015 ( PDF ).

[1] P. Pfeiffer, K. Quehl: About a new effect in solutions of optically active substances (I. Commun.) . In: Reports of the German Chemical Society . tape 64 , no. 10 , 1931, p. 2667–2671 , doi : 10.1002 / cber.19310641015 ( PDF ).