Plakoglobin
| Yup | ||
|---|---|---|
| other names |
Junction plakoglobin; DP3; Catenin (Cadherin-Associated Protein), gamma 80kDa; Desmoplakin III; Desmoplakin-3; ARVD12; CTNNG; PDGB; Catenin gamma; DPIII; PKGB |
|
| Properties of human protein | ||
| Mass / length primary structure | 745 amino acids, 81745 Da | |
| Identifier | ||
| External IDs | ||
| Orthologue | ||
| human | House mouse | |
| Entrez | 3728 | 16480 |
| UniProt | P14923 | Q02257 |
| PubMed search | 3728 |
16480
|
Plakoglobin (synonyms: junction plakoglobin , γ-catenin ) is a structural protein of cell contacts such as desmosomes and adherens junctions . It is homologous to beta-catenin . Plakoglobin binds to cell contacts on the cytosolic side and connects cadherins with the cytoskeleton .
literature
- Jeremy M. Berg, John L. Tymoczko, Lubert Stryer : Biochemistry. 6 edition, Spektrum Akademischer Verlag, Heidelberg 2007, ISBN 978-3-8274-1800-5 .
- Donald Voet, Judith G. Voet: Biochemistry. 3rd edition, John Wiley & Sons, New York 2004, ISBN 0-471-19350-X .
- Bruce Alberts , Alexander Johnson, Peter Walter, Julian Lewis, Martin Raff, Keith Roberts: Molecular Biology of the Cell. 5th edition, Taylor & Francis 2007, ISBN 978-0-8153-4106-2 .
Individual evidence
- ↑ J. Zhurinsky, M. Shtutman, A. Ben-Ze'ev: Plakoglobin and beta-catenin: protein interactions, regulation and biological roles . In: Journal of Cell Science . tape 113 , no. 18 , September 15, 2000, pp. 3127-3139 , PMID 10954412 .