Pulmonary sequester

Classification according to ICD-10
Q33.2	Pulmonary sequestration (congenital)
ICD-10 online (WHO version 2019)

Pulmonary sequesters are lung malformations . The functionless lung sections belong ontogenetically to the lungs, but are independently supplied with blood. Pulmonary sequesters can be the starting point for recurrent infections.

meaning

Pulmonary sequesters are rare. They account for 0.15–6.4% of all pulmonary neoplasms. They develop from excess lung buds during embryogenesis . There is primarily no connection to the bronchial system. Pulmonary sequesters are most frequently found in the area of ​​the left lower lobe of the lung, otherwise mostly in the right posterior lower lobe segment. The arterial blood supply takes place via the thoracic aorta , the outflow via the pulmonary veins (intralobular sequester). With a correspondingly large volume of the supplying vessels, a circulatory-relevant shunt can occur.

Since pulmonary sequesters are primarily not connected to the bronchial system, they are not subject to self-cleaning like the normal lungs. Pathogens can collect and settle here . These entrenched infections lead to melting and a secondary connection to the bronchial system. This leads to recurrent and often therapy-resistant infections of the lungs (e.g. pneumonia ).

If a sequester does not cause symptoms , it is often not recognized at all. If the symptoms are present, sequesters are usually resected. Even if sequesters are discovered by chance, a preventive resection is useful.

Classification

Extralobular sequesters usually manifest in the first year of life. They have their own pleura and often cause recurrent pneumonia.

Intralobular sequesters usually manifest after the age of 20. They do not have their own pleura and often contain mucous plugs. The diagnosis usually requires angiography .

literature

• Elmar Stöcker : About the intralobular sequestration of the lungs . Z. Path. 69: 452-467 (1958).

Individual evidence

1. ^ Prokop, M .: Ganzkörper CT, Thieme, 2007, p. 314

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !