Sensory gating

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Sensory gating is a process of sensory stimulus processing.

The principle of sensory gating is that while a certain stimulus is being processed, the processing of other stimuli that are irrelevant for a particular task is suppressed. The neurophysiological basis is the inhibition of nicotinic acetylcholine receptors and GABA receptors in the thalamus . The measurement is carried out by means of EEG or prepulse inhibition .

Sensory gating can be used as a diagnostic criterion for various neuropsychological diseases such as schizophrenia or Alzheimer's disease .


  1. ^ David A McCormick, Thierry Bal (1994): Sensory gating mechanisms of the thalamus. ( Memento of January 8, 2013 in the Internet Archive ) In: Current Opinion in Neurobiology 1994, 4: 550–556 (PDF; 5.2 MB)
  2. The incomplete suppression of irrelevant information (sensory gating) as a biological marker of cholinergic dysfunction in Alzheimer's dementia. Ruprecht-Karls University Medical Faculty