Subvigilance Syndrome

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Classification according to ICD-10
F51.1 Inorganic hypersomnia
G47.1 Pathologically increased need for sleep, hypersomnia
ICD-10 online (WHO version 2019)

The Subvigilanz syndrome , from Latin sub , 'under and Latin Vigilantia , vigilance' , is a rare form of idiopathic hypersomnia , a sleep addiction . Otherwise healthy sufferers do not feel really awake during the day, although they have slept enough.

It is a proposed, (so far) not recognized clinical picture, it could also be a variant of another drowsiness disorder such as idiopathic hypersomnia.

Synonyms are: English subvigilance syndrome; Subwakefulness syndrome; Sub-wakefulness syndrome

The first description comes from 1972 by Michel Jouvet and JF Pujol.

distribution

The disease is considered to be very rare, around 50 people have been reported to be affected. Both sexes have the same frequency and there is no known family history.

root cause

The cause and triggering factors are not known. A disturbance in wakefulness control or during non-REM sleep is suspected. The neurotransmitter monoamines are also under discussion.

Clinical manifestations

Clinical criteria are:

diagnosis

The following criteria must be present in order to make a diagnosis:

  • A: The person concerned complains of tiredness or excessive need for sleep.
  • B: The symptoms have existed for at least six months.
  • C: The propensity to sleep is mild and neither frequent nor irresistible.
  • D: There has been no traumatic brain injury in the past 18 months .

Additional criteria are:

  • E: The polysomnography shows a normal sleep pattern, the multiple sleep latency test shows a latency of at least 5 minutes.
  • Q: In the 24-hour polysomnography, intermittent fatigue with stage I sleep stages increasing and decreasing throughout the day.
  • G: No organic explanatory cause like hypothyroidism , diabetes mellitus , depression .

Differential diagnosis

Other causes such as idiopathic hypersomnia, narcolepsy , recurrent hypersomnia and menstrual-related sleep disorders, as well as lack of sleep and circadian sleep-wake rhythm disorders, insomnia due to psychophysiological disorders, depression , sleep apnea syndrome or periodic limb movement disorder are to be distinguished . Finally, Kleine Levin syndrome is an option.

literature

  • B. Roth: Narcolepsy and Hypersomnia. Translated by M. Schierlova (Prague). Revised and edited by Broughton, R. (Ottawa). 1980, ISBN 978-3-8055-0490-4 , ISBN 978-3-318-05312-8 , doi: 10.1159 / isbn.978-3-318-05312-8
  • B. Roth: Narcolepsy and hypersomnia: review and classification of 642 personally observed cases. In: Swiss Archives for Neurology, Neurosurgery and Psychiatry = Archives suisses de neurologie, neurosurgery et de psychiatrie. Volume 119, Number 1, 1976, pp. 31-41, PMID 981985 .
  • Bedřich Roth: L'EEG in la narcolepsy cataplexy. In: Electroencephalography and Clinical Neurophysiology. 16, 1964, p. 170, doi: 10.1016 / 0013-4694 (64) 90036-7 .

Individual evidence

  1. ↑ a b c d e f g THE INTERNATIONAL CLASSIFICATION OF SLEEP DISORDERS, REVISED. Diagnostic and Coding Manual Produced by the American Academy of Sleep Medicine American Academy of Sleep Medicine
  2. ^ The Free Dictionary
  3. ↑ American Sleep Apnea Association
  4. ↑ R. Schnell: Objective investigation of hang-over effects with the pupillographic sleepiness test (PST). Inaugural dissertation, Tübingen, 2007 [1]
  5. ^ M. Jouvet, JF Pujol: Role des monoamines dans la regulation de la vigilance. Etude neurophysiologique etbiochimique. In: Revue neurologique. Volume 127, Number 1, July 1972, pp. 115-138, PMID 4358571 .
  6. ↑ a b A. Hisanaga, M. Tsutsumi, S. Yasui, H. Fukuda, H. Tachibana, H. Hagino, A. Okabe, T. Mita, O. Saitoh, M. Kurachi: A case of subwakefulness syndrome. In: Psychiatry and clinical neurosciences. Volume 52, Number 2, April 1998, pp. 206-207, doi: 10.1111 / j.1440-1819.1998.tb01033.x , PMID 9628154 .
  7. ^ WA Broughton, RJ Broughton: Psychosocial impact of narcolepsy. In: Sleep. Volume 17, Number 8 Suppl, December 1994, pp. S45-S49, doi : 10.1093 / sleep / 17.suppl_8.s45 , PMID 7701199 (review).
  8. ↑ JR Mouret, B. Renaud, P. Quenin, D. Michel, B. Schott: Monoamines et regulation de la vigilance. I. Apportet interpretation biochimique des donnees polygraphiques. In: Revue neurologique. Volume 127, Number 1, July 1972, pp. 139-155, PMID 4358572 .
  9. ↑ P. Livrea, FM Puca, A. Barnaba, L. Di Reda: Abnormal Central Monoamine Metabolism in Humans with 'True Hypersomnia' and 'Sub-Wakefulness'. In: European Neurology. 15, 2004, p. 71, doi: 10.1159 / 000114792 , PMID 323018 .